BCL2-Associated Athanogene 2 (

yb310294 产品详细信息
BCL2-Associated Athanogene 2 (BAG2) (C-Term) 抗体
anti-BCL2-Associated Athanogene 2 (BAG2) (C-Term) antibody anti-BCL2-Associated Athanogene 2 (BAG2) (C-Term) antibody (2) anti-BCL2-Associated Athanogene 2 (BAG2) (C-Term) antibody (3)
抗原
BCL2-Associated Athanogene 2 (BAG2)
别名 bag2, MGC89300, BAG2, ATBAG2, BCL-2-associated athanogene 2, MTG10.13, MTG10_13, BAG-2, dJ417I1.2, zgc:64195, 2610042A13Rik, BC016230
抗原表位
其他选择 C-Term
适用
其他选择 小鼠, 大鼠, 犬, 牛, 人, 斑马鱼, 小鸡
宿主
其他选择 兔
克隆类型
多克隆
标记
其他选择 非结合性
应用范围
其他选择 免疫组织化学（IHC）, Western Blotting (WB)
Pubmed 找到1个引用
规格 100 μg
发货至 中国 (更改)
发货时间 9至12个工作日
产品细节 BCL2-Associated Athanogene 2 (BAG2) (C-Term) 抗体
免疫原 Synthetic peptide directed towards the C terminal of human BAG2
序列 VDQKFQSIVI GCALEDQKKI KRRLETLLRN IENSDKAIKL LEHSKGAGSK
预测反应 Bovine : 100 %, Dog : 100 %, Guinea pig : 100 %, Horse : 100 %, Human : 100 %, Mouse : 100 %, Pig : 100 %, Rabbit : 100 %, Rat : 100 %, Zebrafish : 100 %, Chicken : 90 %
产品特性 This is a rabbit polyclonal antibody against BAG2. It was validated on Western Blot and immunohistochemistry.
纯化方法 Protein A purified
目标详细情况 BCL2-Associated Athanogene 2 (BAG2) (C-Term) 抗体
别名 BAG2
背景 BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.
分子量 23 kDa
基因ID 9532
NCBI登录号 NP_004273, NM_004282
UniProt O95816
研究领域 Cancer, Apoptosis/Necrosis
使用细节BCL2-Associated Athanogene 2 (BAG2) (C-Term) 抗体
应用备注 Optimal working dilutions should be determined experimentally by the investigator.
说明
Antigen size: 211 AA
限制 仅限研究用
贮存及处理BCL2-Associated Athanogene 2 (BAG2) (C-Term) 抗体
状态 Lyophilized
溶解方式 Add 100 µL of distilled water.
浓度 1 mg/mL
缓冲液 PBS buffer with 2 % sucrose
注意事项 Avoid repeated freeze-thaw cycles.
储存条件 -20 °C
储存方法 For longer periods of storage, store at -20 °C
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