Clusterin (CLU) 抗体

yb238421 产品详细信息
Clusterin (CLU) 抗体
anti-Clusterin (CLU) antibody
抗原
Clusterin (CLU)
别名
LOC100136120, clu, MGC53055, zgc:73352, xclu, MGC89163, CLU, APO-J, APOJ, CLI, CLU1, CLU2, KUB1, NA1/NA2, SGP-2, SGP2, SP-40, TRPM-2, TRPM2, DAG, RATTRPM2B, SP40, TRPM2B, Trpm2, Trpmb, AI893575, ApoJ, ... show more
适用
其他选择 人
宿主
其他选择 小鼠
克隆类型 (克隆位点)
单克隆 (Hs-3)
标记
其他选择 非结合性
应用范围
其他选择 酵素免疫分析法（EIA）, 免疫萤光（IF）, Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)), Western Blotting (WB), 免疫组织化学石蜡技术（IHC-P）
Pubmed 6个引用可参考
规格 0.1 mg
发货至 中国 (更改)
发货时间 29至35个工作日
产品细节Clusterin (CLU) 抗体
免疫原 Freshly ejaculated human sperms were washed in PBS and extracted in 3% acetic acid,10% glycerol, 30 mM benzaminidine. The acid extract was dialyzed against 0. 2% acetic acid and subsequently used forimmunization.
克隆位点 Hs-3
亚型 IgG1
特异性 Recognizes Apolipoprotein J (Apo J).
交叉反应 （详细） Species reactivity (tested):Human. Negative in Bovine, Canine (Dog) and Feline (Cat).
产品特性 Synonyms: Clusterin, APOJ, CLI, KUB1, AAG4, NA1/NA2, SP-40, 40, Complement-associated proteinSP-40, Complement cytolysis inhibitor, Testosterone-repressed prostate message 2,Ku70-binding protein 1, Aging-associated gene 4 protein
纯化方法 Affinity Chromatography on Protein A
目标详细情况 Clusterin (CLU) 抗体
别名 Apolipoprotein J (Apo J)
背景 Clusterin (APO J, SGP-2, TRPM-2, SP-40, pADHC-9, CLJ, T64, GP III, XIP8) is a 75-80 kD disulfide-linked heterodimeric protein containing about 30 % of N-linked carbohydrate rich in sialic acid but truncated forms targeted to the nucleus have also been identified. It is a conserved secreted glycoprotein expressed by a wide range of tissues and being implicated in many physiological processes, including e.g. lipid transportation, complement inhibition, tissue remodeling, membrane recycling, or clearence of cellular debris. It is nearly ubiqitously expressed in most mammalian tissues and can be found in plasma, milk, urine, cerebrospinal fluid and semen. Clusterin is able to bind and form complexes with numerous partners (immunoglobulins, lipids, heparin, bacteria, complement components, paraoxonase, beta amyloid, leptin etc.) and is expressed in many pathological and clinically relevant situations including cancer, organ regeneration, infection, Alzheimer disease, retinitis pigmentosa, myocardial infarction, renal tubular damage, autoimmunity and others. A genuine function of clusterin is still enigmatic.Synonyms: 40, 40, AAG4, APOJ, Aging-associated gene 4 protein, CLI, Clusterin, Complement cytolysis inhibitor, Complement-associated protein SP-40, KUB1, Ku70-binding protein 1, NA1/NA2, SP-40, Testosterone-repressed prostate message 2
基因ID 1191
UniProt P10909
研究领域 Metabolism, Receptors
使用细节Clusterin (CLU) 抗体
应用备注 ELISA. Western blot: 1/ μg/mLPositive Material: seminal plasmaImmunocytochemistry. Immunohistochemistry on Paraffin Sections: 10 μg/mL. Positive Tissue: Sertoli cells.
限制 仅限研究用
贮存及处理 Clusterin (CLU) 抗体
浓度 1.0 mg/mL
缓冲液 PBS, pH ~7.4 with 15 mM Sodium Azide as preservative
储存液 Sodium azide
注意事项 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件 4 °C/-20 °C
储存方法 Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
有效期 12 months