Importin 11 (IPO11) (C-Term),

Importin 11 (IPO11) (C-Term), (AA 891-920) 抗体抗原
Importin 11 (IPO11)
别名 MGC83107, IPO11, slrn, ranbp11, RanBP11, 1700081H05Rik, 2510001A17Rik, AI314624, AW555235, E330021B14Rik, Ranbp11
抗原表位
其他选择 C-Term, AA 891-920
适用
其他选择 人
宿主
其他选择 兔
克隆类型 (克隆位点)
多克隆 (RB24373)
标记
其他选择 非结合性
应用范围
其他选择 Western Blotting (WB)
Pubmed 找到1个引用
规格 400 μL
发货至 中国 (更改)
发货时间 9至13个工作日
产品编号 yb653614
产品细节 Importin 11 (IPO11) (C-Term), (AA 891-920) 抗体
免疫原 This IPO11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 891-920 AA from the C-terminal region of human IPO11.
克隆位点 RB24373
亚型 Ig
特异性 This IPO11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 906~970 amino acids from the C-terminal region of human IPO11.
预测反应 Mouse (Murine)
纯化方法 This antibody is purified through a protein A column, followed by peptide affinity purification.
目标详细情况 Importin 11 (IPO11) (C-Term), (AA 891-920) 抗体
别名 IPO11
背景 IPO11 functions in nuclear protein import as nuclear transport receptor. It serves as receptor for nuclear localization signals (NLS) in cargo substrates and is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP-and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity). It mediates the nuclear import of UBE2E3, and of RPL12 (By similarity).
Synonyms: Ran-binding protein 11, RanBP11, Importin-11, Imp11, IPO11, RANBP11
分子量 112535 DA
基因ID 51194
UniProt Q9UI26
研究领域 Signaling, Cancer, Neurology, Cell Structure
使用细节 Importin 11 (IPO11) (C-Term), (AA 891-920) 抗体
应用备注 WB = 1:1000
限制 仅限研究用
贮存及处理 Importin 11 (IPO11) (C-Term), (AA 891-920) 抗体
状态 Liquid
浓度 0.5 mg/mL
缓冲液 PBS with 0.09 % (W/V) sodium azide
储存液 Sodium azide
注意事项 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件 4 °C/-20 °C
储存方法 Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
有效期 6 months