LC3 (APG8B) (AA 1-30), (Thr6)

LC3 (APG8B) (AA 1-30), (Thr6) 抗体抗原
LC3 (APG8B)
抗原表位
其他选择 AA 1-30, Thr6
适用
其他选择 人, 小鼠
宿主
其他选择 兔
克隆类型 (克隆位点)
多克隆 (RB17593)
应用范围
其他选择 Western Blotting (WB)
Pubmed 5个引用可参考
规格 400 μL
发货至 中国 (更改)
发货时间 9至13个工作日
产品编号 yb388475
产品细节 LC3 (APG8B) (AA 1-30), (Thr6) 抗体
免疫原 This LC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 AA from human LC3.
克隆位点 RB17593
亚型 Ig
特异性 This LC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1~30 amino acids surrounding T6 of human MAP1LC3B.
预测反应 Cow (Bovine)
纯化方法 This antibody is purified through a protein A column, followed by peptide affinity purification.
目标详细情况LC3 (APG8B) (AA 1-30), (Thr6) 抗体
背景 Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. These proteins are involved in formation of autophagosomal vacuoles (autophagosomes). MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. MAP1LC3b is one of the light chain subunits and can associate with either MAP1A or MAP1B. The precursor molecule is cleaved by APG4B/ATG4B to form the cytosolic form, LC3-I. This is activated by APG7L/ATG7, transferred to ATG3 and conjugated to phospholipid to form the membrane-bound form, LC3-II.
Synonyms: MAP1LC3B, LC3B, MAP1A/1BLC3, MAP1LC3B
分子量 14557 DA
基因ID 81631
UniProt Q9GZQ8
研究领域 Cell Signaling, Cell Structure, Autophagy
使用细节 LC3 (APG8B) (AA 1-30), (Thr6) 抗体
应用备注 WB = 1:1000
限制 仅限研究用
贮存及处理 LC3 (APG8B) (AA 1-30), (Thr6) 抗体
状态 Liquid
浓度 0.5 mg/mL
缓冲液 PBS with 0.09 % (W/V) sodium azide
储存液 Sodium azide
注意事项 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件 4 °C/-20 °C
储存方法 Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
有效期 6 months