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- 保存条件：
-20℃
- 克隆性：
单克隆
- 抗体名：
CD209 Molecule (CD209) 抗体 (Biotin)
- 规格：
0.1ml/0.2ml
CD209 Molecule (CD209)
别名 cd209, CLEC4M, DC-SIGN, si:ch211-224h1.3, CDSIGN, CLEC4L, DC-SIGN1, CD209, CIRE, Dcsign, SIGN-R1, SIGNR5, Cd209
适用
其他选择 人
宿主
其他选择 小鼠
克隆类型 (克隆位点)
单克隆 (MR-1)
标记
其他选择 Biotin
应用范围
其他选择 流式细胞分析技术（FACS）
Pubmed 2个引用可参考
规格 0.1 mg
发货至 中国 (更改)
发货时间 29至35个工作日
产品编号 yb181972
产品细节 CD209 Molecule (CD209) 抗体 (Biotin)
免疫原 Immature myeloid monocyte-derived dendritic cells (MDDCs). Spleen cells from immunised Balb/c mice were fused with cells of the Mouse SP2/0-Ag14 myeloma cell line.
克隆位点 MR-1
亚型 IgG1
特异性 This antibody recognises DC-specific ICAM-3 grabbing nonintegrin (DC-SIGN), a 45 kDa C-type lectin that binds ICAM-3 which is also known as CD209. Clone MR-1 is reported to partially block the functional activity of DC-SIGN. We recommend the use of SM2219LE for this purpose.
纯化方法 Affinity chromatography on Protein G
目标详细情况 CD209 Molecule (CD209) 抗体 (Biotin)
别名 CD209 / DC-SIGN
背景 CD209 is primarily expressed on a population of immature dendritic cells in peripheral tissues and on immature myeloid monocyte-derived DC's in vitro. CD209 is involved in dendritic cell (DC) migration and the initial interaction between DC's and naive T lymphocytes. CD209 also binds HIV-1 gp120 and plays a key role in the dissemination of HIV-1 by DC's.Synonyms: C-type lectin domain family 4 member L, CLEC4L, DC-SIGN1, DCSIGN, DCSIGN1, Dendritic Cell Marker, Dendritic cell-specific ICAM-3-grabbing non-integrin 1
基因ID 9606
UniProt Q9NNX6
研究领域 CD Antigens
使用细节 CD209 Molecule (CD209) 抗体 (Biotin)
应用备注 Flow Cytometry: Neat - 1/10, Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
限制 仅限研究用
贮存及处理 CD209 Molecule (CD209) 抗体 (Biotin)
浓度 0.1 mg/mL
缓冲液 PBS, pH 7.4 containing 0.09 % Sodium Azide and 1 % Bovine Serum Albumin
储存液 Sodium azide
注意事项 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项 Avoid repeated freezing and thawing.
储存条件 4 °C/-20 °C
储存方法 Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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文献和实验上皮及间皮类常用标记抗体EPITHELIAL AND MESOTHELIAL MARKERSCK (MNF 116)- MNF-116 is a pan-cytokeratin antibody.- Source: Dakopatts.- Dilution 1:50.- Antigen retrieval method: HIER (pressure cooking) using EDTA.- Staining pattern: Cytoplasmic, typically
结合介导感染。而ACE2是局部高血压蛋白酶原-血管紧张素系统的负调控蛋白，可保护肺泡的实验性损伤。SARS-CoV感染可下调肺部ACE2水平，加剧肺损伤。SRAS也可能通过另一细胞受体C-lectin-CD209(DC-SIGN)和CD209L(DC-SIGNR)感染免疫细胞，IX；可能参与了病毒感染与抗原提呈过程。 固有免疫不足以清除病毒感染，而在抗SARS-CoY适应性免疫诱导过程中，发现感染第10日患者体内病毒达到高峰，15d后病毒逐渐下降，21 d可测特异性IgM
Hybridization to Dissected Gonads with Digoxygenin-Labeled Probes ・ Chromosome In Situ Hybridization Using Biotin Labeled Probes (Carthew Lab) ・ In-Situ Hybridization to mRNA using radiolabelled cRNA probes (Beverly Faulkner
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