Integrin beta 4 (ITGB4) 抗体

Integrin beta 4 (ITGB4) 抗体抗原
Integrin beta 4 (ITGB4)
别名 AA407042, C230078O20, CD104
适用
其他选择 人
宿主
其他选择 小鼠
克隆类型 (克隆位点)
单克隆 (450-9D)
标记
其他选择 非结合性
应用范围
其他选择 Immunohistochemistry (Frozen Sections) (IHC (fro)), 流式细胞分析技术（FACS）, 免疫沉淀（IP）, Western Blotting (WB)
Pubmed 找到1个引用
规格 0.2 mg
发货至 中国 (更改)
发货时间 29至35个工作日
产品编号 yb118872
产品细节 Integrin beta 4 (ITGB4) 抗体
免疫原 Purified alpha 6/beta 4 Integrin from A431 cells. Spleen cells from immunised BALB/c mice were fused with cells of the mouse Sp2/0 myeloma cell line.
克隆位点 450-9D
亚型 IgG1
特异性 This antibody reacts with beta 4 Integrin (CD104). This antibody recognises an extracellular epitope on the CD104 Molecule.
交叉反应 （详细） Species reactivity (tested):Human.
纯化方法 Affinity Chromatography on Protein G.
目标详细情况 Integrin beta 4 (ITGB4) 抗体
别名 CD104 / Integrin beta-4
背景 Integrin beta 4 is a glycoprotein which associates with the a6 integrin to form the a6/b4 complex. Integrin alpha 6/beta 4 is a receptor for laminin. It plays a critical structural role in the hemidesmosome of epithelial cells. Defects in Integrin beta 4 gene are a cause of epidermolysis bullosa letalis with pyloric atresia (EB PA), also known as junctional epidermolysis bullosa with pyloric atresia (PA-JEB) or aplasia cutis congenita with gastrointestinal atresia. EB-PA is characterized by mucocutaneous fragility and gastrointestinal atresia, which most commonly affects the pylorus. Moreover, defects in Integrin beta 4 gene are a cause of generalized atrophic benign epidermolysis bullosa (GABEB). This nonlethal form of junctional epidermolysis bullosa is characterized by life long blistering of the skin, associated with hair and tooth abnormalities. CD104 is expressed on epithelial cells, Schwann cells and some tumor cell lines.Synonyms: GP150, ITGB4
基因ID 3691
NCBI登录号 NP_000204
UniProt P16144
使用细节 Integrin beta 4 (ITGB4) 抗体
应用备注 Flow Cytometry (1/25-1/100): Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. Immunoprecipitation. Western blot. Immunohistochemistry on Frozen Sections (1/500-1/1000). Does not work on Paraffin Sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
限制 仅限研究用
贮存及处理 Integrin beta 4 (ITGB4) 抗体
浓度 1.0 mg/mL
缓冲液 PBS, pH 7.4, containing 0.09 % Sodium Azide as preservative.
储存液 Sodium azide
注意事项 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项 Avoid repeated freezing and thawing.
储存条件 4 °C/-20 °C
储存方法 Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.