CD53 (CD53) 抗体

CD53 (CD53) 抗体抗原
CD53 (CD53)
别名 AI323659, Ox-44, Tspan25, MOX44, TSPAN25, OX44
适用
其他选择 人
宿主
其他选择 小鼠
克隆类型 (克隆位点)
单克隆 (MEM-53)
标记
其他选择 非结合性
应用范围
其他选择 Immunohistochemistry (Frozen Sections) (IHC (fro)), 流式细胞分析技术（FACS）, 免疫沉淀（IP）, Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)), Western Blotting (WB), 免疫组织化学石蜡技术（IHC-P）
Pubmed 2个引用可参考
规格 0.2 mg
发货至 中国 (更改)
发货时间 29至35个工作日
产品编号 yb118729
产品细节 CD53 (CD53) 抗体
克隆位点 MEM-53
亚型 IgG1
交叉反应 （详细） Species reactivity (tested):Human.
纯化方法 Affinity Chromatography on Protein G
目标详细情况 CD53 (CD53) 抗体
别名 CD53
背景 CD53 is a member of the tetraspan family of molecules, and is expressed by all leucocytes, but is absent from red cells and platelets. Most of the tetraspan family of molecules are cell surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. CD53 is a cell surface glycoprotein that is known to complex with integrins. It contributes to the transduction of CD2 generated signals in T cells and natural killer cells and has been suggested to play a role in growth regulation. Familial deficiency of this gene has been linked to an immunodeficiency associated with recurrent infectious diseases caused by bacteria, fungi and viruses. CD53 is a glycoprotein of 32-40 kDa belonging to the tetraspans family (TM4SF). CD53 antigen is exclusivelly expressed on leucocytes (not present on platelets, red blood cells and non-hematopoietic cells). CD53 is important for signal transduction. CD53 cross-linking promotes activation of human B cells and rat macrophages.Synonyms: Cell surface glycoprotein CD53, Leukocyte surface antigen CD53, MOX44, TSPAN25, Tetraspanin-25
基因ID 963
NCBI登录号 NP_000551
UniProt P19397
研究领域 CD Antigens, Surface Receptors of Immune Cells
使用细节 CD53 (CD53) 抗体
应用备注 Flow cytometry: 1/10 - 1/25, use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. Immunoprecipitation. Immunohistochemistry on frozen sections. Western blotting under non-reducing conditions.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
限制 仅限研究用
贮存及处理CD53 (CD53) 抗体
浓度 1.0 mg/mL
缓冲液 PBS, pH 7.4 containing 0.09 % Sodium Azide
储存液 Sodium azide
注意事项 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项 Avoid repeated freezing and thawing.
储存条件 4 °C/-20 °C
储存方法 Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.