Integrin alpha 1 (ITGA1) 抗体 (F

Integrin alpha 1 (ITGA1) 抗体 (FITC)抗原
Integrin alpha 1 (ITGA1)
别名 CD49A, E130012M19Rik, Vla1, CD49a, VLA1
适用
其他选择 人
宿主
其他选择 小鼠
克隆类型 (克隆位点)
单克隆 (TS2-7)
标记
其他选择 FITC
应用范围
其他选择 流式细胞分析技术（FACS）
Pubmed 3个引用可参考
规格 0.1 mg
发货至 中国 (更改)
发货时间 29至35个工作日
产品编号 yb118691
产品细节 Integrin alpha 1 (ITGA1) 抗体 (FITC)
克隆位点 TS2-7
亚型 IgG1
纯化方法 Affinity Chromatography on Protein G.
目标详细情况 Integrin alpha 1 (ITGA1) 抗体 (FITC)
别名 CD49a / ITGA1
背景 Integrins are important extracellular matrix (ECM) receptor proteins located on cell surfaces. They are hetrodimers composed of an alpha and a beta transmembrane glycoprotein subunit. Around twenty two different integrins (different alpha/ beta subunit combinations) are found in nature. Integrins are generally present in high concentrations at the cell surface, but, unlike most other cell surface receptors, they bind ligands with very low affinity. Due to their weak individual binding, integrins need to cluster and bind in groups in order to effectively bind the ECM. Integrins bind many different ligands including laminin. Each integrin is made up of a large N terminal extracellular domain that binds the ECM ligand and a small C terminal cytoplasmic domain that mediates interaction with the actin cytoskeleton and signaling function. Alpha 1 integrin along with alpha 2, alpha L and alpha M has a unique inserted domain. Integrin alpha 1 is a receptor for laminin and collagen. The alpha1 subunit is also known as CD49a. CD49a associates with CD29 (beta 1 integrin), to form an alpha1 beta1 heterodimer, identified as the rat homologue to VLA1, which is involved in cellular adhesion to laminin and collagen.Synonyms: CD49 antigen-like family member A, ITGA-1, Integrin alpha-1, Laminin and Collagen Receptor, VLA-1, VLA1
基因ID 3672
NCBI登录号 NP_852478
UniProt P56199
研究领域 CD Antigens, Surface Receptors of Immune Cells
使用细节Integrin alpha 1 (ITGA1) 抗体 (FITC)
应用备注 Flow cytometry: Neat-1/5, Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
限制 仅限研究用
贮存及处理 Integrin alpha 1 (ITGA1) 抗体 (FITC)
浓度 0.1 mg/mL
缓冲液 PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative and 1 % BSA as stabilizer.
储存液 Sodium azide
注意事项 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项 Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light
储存条件 4 °C/-20 °C
储存方法 Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.