Chemokine (C-C Motif) Ligand 2

Chemokine (C-C Motif) Ligand 2 (CCL2) (C-Term) 抗体抗原
Chemokine (C-C Motif) Ligand 2 (CCL2)
别名 MCP-1, Scya2, Sigje, GDCF-2, HC11, HSMCR30, MCAF, MCP1, SCYA2, SMC-CF, AI323594, JE, MCP-1A, MCP1A
抗原表位
其他选择 C-Term
适用
其他选择 人
宿主
其他选择 兔
克隆类型
多克隆
标记
其他选择 非结合性
应用范围
其他选择 酵素免疫分析法（EIA）, Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)), Western Blotting (WB), 免疫组织化学石蜡技术（IHC-P）
Pubmed 2个引用可参考
规格 0.4 mL
发货至 中国 (更改)
发货时间 29至35个工作日
产品编号 yb452821
产品细节 Chemokine (C-C Motif) Ligand 2 (CCL2) (C-Term) 抗体
免疫原 KLH conjugated synthetic peptide selected from the C-terminal region of human CCL2
特异性 This antibody detects MCP1 / CCL2 at C-term.
交叉反应 （详细） Species reactivity (tested):Human
纯化方法 Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
目标详细情况 Chemokine (C-C Motif) Ligand 2 (CCL2) (C-Term) 抗体
别名 MCP1 / CCL2
背景 Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. CCL2 is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4.Synonyms: C-C motif chemokine 2, HC-11, HC11, MCAF, MCP-1, Monocyte chemoattractant protein 1, Monocyte chemotactic and activating factor, Monocyte chemotactic protein 1, Monocyte secretory protein JE, SCYA2, Small-inducible cytokine A2
分子量 11025 Da
基因ID 6347
NCBI登录号 NP_002973
UniProt P13500
研究领域 Cytokines, Chemokines
使用细节 Chemokine (C-C Motif) Ligand 2 (CCL2) (C-Term) 抗体
应用备注 Western blot: 1: 50 - 1: 100. ELISA: 1: 1,000. Immunohistochemistry on paraffin sections: 1: 50 - 1: 100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
限制 仅限研究用
贮存及处理Chemokine (C-C Motif) Ligand 2 (CCL2) (C-Term) 抗体
状态 Liquid
浓度 0.25 mg/mL
缓冲液 PBS with 0.09 % (W/V) sodium azide
储存液 Sodium azide
注意事项 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项 Avoid repeated freezing and thawing.
储存条件 4 °C/-20 °C
储存方法 Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.