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文献和实验Adjuvant Activity of Cytokines
The activity of several potent adjuvants, including incomplete Freund’s adjuvant, CpG oligodeoxynucleotides, and alum, has been shown to be due at least in part to the induction of cytokines, including type I interferons (IFNs), IFN
Aluminum Compounds as Vaccine Adjuvants
(7 ) and differ in their adjuvant properties (3 ,6 ); and (2) alum, chemically potassium aluminum sulfate (KAl(SO4 )2 .12H2 O), has not been used as an adjuvant as such. Alum was originally used to partially purify protein antigens, mainly tetanus and diphtheria
Virus-like Particles As Vaccine Adjuvants
of one or more viral coat proteins can act as an adjuvant by carrying peptide sequences inside the APC and feeding into the “endogenous” processing pathway (2 ,3 ), a phenomemon known as “cross-priming.” No additional adjuvant is needed. If VLPs are administered
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