Forkhead Box O1 (FOXO1) (AA 254-258) 抗体抗原
Forkhead Box O1 (FOXO1)
别名 FOXO1, FOXO1A, fkh1, fkhr, foxo1a, xFoxO1, FKH1, FKHR, AI876417, Afxh, Fkhr1, Foxo1a, Fkhr, FoxO1A, FoxO1a.1, foxo1, zgc:153388
抗原表位
其他选择 AA 254-258
适用
其他选择 人
宿主
其他选择 兔
克隆类型
多克隆
标记
其他选择 非结合性
应用范围
其他选择 免疫萤光(IF), Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)), Western Blotting (WB), 免疫组织化学石蜡技术(IHC-P)
Pubmed 5个引用可参考
规格 50 μL
发货至 中国 (更改)
发货时间 29至35个工作日
产品编号 yb197335
产品细节 Forkhead Box O1 (FOXO1) (AA 254-258) 抗体 免疫原 Peptide Sequence around amino acids 254~258 (A-A-S-M-D) derived from Human FKHR/FOXO1A
特异性 This antibody detects endogenous levels of total FKHR protein.
交叉反应 (详细) Species reactivity (tested):Human tissue and cell lines
纯化方法 Immunoaffinity Chromatography using epitope-specific immunogen.
目标详细情况 Forkhead Box O1 (FOXO1) (AA 254-258) 抗体 别名 FOXO1A
背景 FOXO1A (FKHR or ForkHead in Rhabdomyosarcoma) is a 70 kDa protein which is a member of a subfamily of the forkhead homeotic gene family of transcription factors. Recent studies have shown that this protein can act as either a coactivator or a corepressor of nuclear receptor activity. This action is mediated through the LXXLL motif found in the C terminus of the FOXO1A protein. The specific function of the gene has not yet been determined, however, it may play a role in myogenic growth and differentiation. Chromosomal aberrations involving FOXO1A are a cause of rhabdomyosarcoma 2 (RMS2), also known as alveolar rhabdomyosarcoma.Synonyms: FKHR, FOXO1, Forkhead Box Protein O1, Forkhead Box Protein O1A, Forkhead in Rhabdomyosarcoma
分子量 78-82 KDa
基因ID 2308
NCBI登录号 NP_002006
UniProt Q12778
研究领域 Cancer, Transcription Factors
使用细节 Forkhead Box O1 (FOXO1) (AA 254-258) 抗体 应用备注 Western blot: 1/500-1/1000. Immunofluorescence: 1/100-1/200. Immunohistochemistry on Paraffin-Embedded Sections: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
限制 仅限研究用
贮存及处理 Forkhead Box O1 (FOXO1) (AA 254-258) 抗体 浓度 1.0 mg/mL
缓冲液 PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.
储存液 Sodium azide
注意事项 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项 Avoid repeated freezing and thawing.
储存条件 -20 °C
储存方法 Store the antibody (in aliquots) at -20 °C.