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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
peptide corresponding to a sequence at the C-terminus of human Hamartin.
- 亚型:
Rabbit Polyclonal IgG
- 形态:
液态
- 保存条件:
保存于-20℃
- 克隆性:
多克隆
- 标记物:
无标记(PLlabs可供应生物素、酶、荧光素标记的抗体)
- 适应物种:
Hu,Mo,Rat
- 保质期:
按说明书条件可保存1-2年
- 抗原来源:
见详细说明资料
- 目录编号:
PL0402656
- 级别:
超纯
- 库存:
大量
- 供应商:
华拓生物
- 宿主:
Rabbit
- 应用范围:
WB: 1:100-500 IHC: 1:500-1000
- 浓度:
1mg/ml
- 靶点:
TSC1
- 抗体英文名:
TSC1 Antibody
- 抗体名:
TSC1抗体
- 规格:
0.1ml
Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background:
This product for research use only, not for use in humans, therapeutic or diagnostic procedures.
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文献和实验Tissue-Specific Ablation of Tsc1 in Pancreatic Beta-Cells
Tuberous sclerosis complex 1 (TSC1) is a tumor suppressor that associates with TSC2 to inactivate Rheb, thereby inhibiting signaling by the mammalian target of rapamycin (mTOR) complex 1 (mTORC1). mTORC1 stimulates cell growth by promoting
Generation of Antibody Molecules Through Antibody Engineering
been overcome to a large extent using genetic-engineering techniques to produce chimeric mouse/human and completely human antibodies. Such an approach is particularly suitable because of the domain structure of the antibody molecule ( 2 ), where functional
is associated with some of the most severe clinical problems of TSC, including epilepsy, intellectual disability, and abnormal behavioral phenotypes. Inactivating mutations have been identified in two disease-causing genes, TSC1 on chromosome 9q34 (MIM *191100
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