- ￥2400
- PLLABS
- 加拿大
- PL0402428
- 2025年07月11日
- WB: 1:100-500 IHC: 1:500-1000
- Rabbit
- Hu，Mo，Rat
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- 详细信息
- 技术资料
- 免疫原：
peptide corresponding to a sequence in the middle region of human HEXA.
- 亚型：
Rabbit Polyclonal IgG
- 形态：
液态
- 保存条件：
保存于-20℃
- 克隆性：
多克隆
- 标记物：
无标记（PLlabs可供应生物素、酶、荧光素标记的抗体）
- 适应物种：
Hu，Mo，Rat
- 保质期：
按说明书条件可保存1-2年
- 抗原来源：
见详细说明资料
- 目录编号：
PL0402428
- 级别：
超纯
- 库存：
大量
- 供应商：
华拓生物
- 宿主：
Rabbit
- 应用范围：
WB: 1:100-500 IHC: 1:500-1000
- 浓度：
1mg/ml
- 靶点：
HEXA
- 抗体英文名：
HEXA Antibody
- 抗体名：
HEXA抗体
- 规格：
0.1ml
HEXA Antibody
Cat#：PL0402428
Isotype:Rabbit Polyclonal IgG
Immunogen：peptide corresponding to a sequence in the middle region of human HEXA.
Purification: Immunogen affinity purified
Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background：
Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background：
HEXA(hexosaminidase A(alpha polypeptide)) is an enzyme that in humans is encoded by the HEXA gene. Hexosaminidase A and the cofactor GM2 activator protein catalyze the degradation of the GM2 gangliosides and other molecules containing terminal N-acetyl hexosamines The HEXA gene encodes the alpha subunit of hexosaminidase A, a lysosomal enzyme involved in the breakdown of gangliosides. The HEXA gene is mapped on 15q23. Even though the alpha and beta subunits of hexosaminidase A can both cleave GalNAc residues, only the alpha subunit is able to hydrolyze GM2 gangliosides. The alpha subunit contains a key residue, Arg-424, which is essential for binding the N-acetyl-neuramanic residue of GM2 gangliosides. Chimeric constructs were expressed in HeLa cells and selected constructs were produced in the baculovirus expression system to determine their ability to degrade GM2 ganglioside in the presence of GM2 activator protein.
Alternate Names：
Beta hexosaminidase alpha chain precursor antibody;Beta hexosaminidase subunit alpha antibody;Beta N acetylhexosaminidase antibody;Beta N acetylhexosaminidase subunit alpha antibody;Beta-hexosaminidase subunit alpha antibody.
Specificity Reaction：Hu，Mo，Rat
Application Notes:WB: 1:100-500 IHC: 1:500-1000
Storage ：
Store at –20ºC for one year. Avoid repeated freeze-thaw cycles. At 4ºC for 2-3 weeks after reconstituted.
This product for research use only, not for use in humans, therapeutic or diagnostic procedures.
PLlabs公司可供应相应抗体的生物素、辣根过氧化物酶、荧光素（FITC、PE、 CY3、 CY5、 CY7、 PE- CY3/5/7)标记抗体，欢迎大家咨询订购。
PLLABS坚持提供高质量的产品和专业的技术服务，并提供完善的技术支持和售后服务。
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HEXA Antibody
￥2400
