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CD146 Antibody

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  • ¥2400
  • PLLABS已认证
  • 加拿大
  • 2026年01月13日
  • WB: 1:100-500 IHC: 1:500-1000
  • Rabbit
  • Hu,Mo,Rat
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 免疫原

      peptide corresponding to a sequence at the C-terminus of human CD146.

    • 亚型

      Rabbit Polyclonal IgG

    • 形态

      液态

    • 保存条件

      保存于-20℃

    • 克隆性

      多克隆

    • 标记物

      无标记(PLlabs可供应生物素、酶、荧光素标记的抗体)

    • 适应物种

      Hu,Mo,Rat

    • 保质期

      按说明书条件可保存1-2年

    • 抗原来源

      见详细说明资料

    • 目录编号

      PL0402376

    • 级别

      超纯

    • 库存

      大量

    • 供应商

      华拓生物

    • 宿主

      Rabbit

    • 应用范围

      WB: 1:100-500 IHC: 1:500-1000

    • 浓度

      1mg/ml

    • 靶点

      CD146

    • 抗体英文名

      CD146 Antibody

    • 抗体名

      CD146抗体

    • 规格

      0.1ml

    产品细节图片1
    CD146 Antibody
    Cat#:PL0402376
    Isotype:Rabbit Polyclonal IgG
    Immunogen:peptide corresponding to a sequence at the C-terminus of human CD146.
    Purification: Immunogen affinity purified

    Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)

    Background:
    CD146(cluster of differentiation 146) also known as the melanoma cell adhesion molecule(MCAM) or cell surface glycoprotein MUC18, is a 113kDa cell adhesion molecule currently used as a marker for endothelial cell lineage. In humans, the CD146 protein is encoded by the MCAM gene. By radiation hybrid analysis, Kuske and Johnson(1999) mapped the CD146 gene to chromosome 11q23.3. It is a member of the immunoglobulin superfamily, is homologous to several cell adhesion molecules and is associated with tumor progression and the development of metastasis in human malignant melanoma. CD146 has been demonstrated to appear on a small subset of T and B lymphocytes in the peripheral blood of healthy individuals. The CD146+ T cells display an immunophenotype consistent with effector memory cells and have a distinct gene profile from the CD146- T cells.
    Alternate Names:
    A32 antigen antibody;CD146 antibody;CD146 antigen antibody;Cell surface glycoprotein MUC18 antibody;Cell surface glycoprotein P1H12 antibody;Gicerin antibody;MCAM antibody;Melanoma adhesion molecule antibody;Melanoma associated antigen A32 antibody.
    Specificity Reaction:Hu,Mo,Rat
    Application Notes:WB: 1:100-500 IHC: 1:500-1000
    Storage :
    Store at –20ºC for one year. Avoid repeated freeze-thaw cycles. At 4ºC for 2-3 weeks after reconstituted.

    This product for research use only, not for use in humans, therapeutic or diagnostic procedures.
    PLlabs公司可供应相应抗体的生物素、辣根过氧化物酶、荧光素(FITC、PE、 CY3、 CY5、 CY7、 PE- CY3/5/7)标记抗体,欢迎大家咨询订购。

    产品细节图片2 产品细节图片3 产品细节图片4
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    图标文献和实验
    相关实验
    • 人可溶性CD146(sCD146)酶联免疫分析(ELISA)

      人 可溶性CD146(sCD146) 酶联免疫分析( ELISA ) 试剂盒使用说明书 本试剂仅供研究使用         目的:本试剂盒用于测定人血清,血浆及相关液体样本中可溶性CD146(sCD146) 含量。 实验原理:     本试剂盒应用双抗体夹心法测定标本中人可溶性 CD146(sCD146) 水平。用纯化的人可溶性 CD146(sCD146) 抗体包被微孔板,制成固相抗体,往包被单抗的微孔中依次加入

    • Generation of Antibody Molecules Through Antibody Engineering

      been overcome to a large extent using genetic-engineering techniques to produce chimeric mouse/human and completely human antibodies. Such an approach is particularly suitable because of the domain structure of the antibody molecule ( 2 ), where functional

    • The Antibody Molecule

      The importance of antibody molecules was first recognized in the 1890s, when it was shown that immunity to tetanus and diphtheria was caused by antibodies against the bacterial exotoxins (1 ). Around the same time, it was shown that antisera

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