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Fascin Antibody

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  • ¥2400
  • PLLABS已认证
  • 加拿大
  • PL0402214
  • 2025年07月09日
  • WB: 1:100-500
  • Rabbit
  • Hu,Mo,Rat
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 免疫原

      peptide corresponding to a sequence at the N-terminus of human Fascin.

    • 亚型

      Rabbit Polyclonal IgG

    • 形态

      液态

    • 保存条件

      保存于-20℃

    • 克隆性

      多克隆

    • 标记物

      无标记(PLlabs可供应生物素、酶、荧光素标记的抗体)

    • 适应物种

      Hu,Mo,Rat

    • 保质期

      按说明书条件可保存1-2年

    • 抗原来源

      见详细说明资料

    • 目录编号

      PL0402214

    • 级别

      超纯

    • 库存

      大量

    • 供应商

      华拓生物

    • 宿主

      Rabbit

    • 应用范围

      WB: 1:100-500

    • 浓度

      1mg/ml

    • 靶点

      Fascin

    • 抗体英文名

      Fascin Antibody

    • 抗体名

      Fascin抗体

    • 规格

      0.1ml

    产品细节图片1
    Fascin Antibody
    Cat#:PL0402214
    Isotype:Rabbit Polyclonal IgG
    Immunogen:peptide corresponding to a sequence at the N-terminus of human Fascin.
    Purification: Immunogen affinity purified

    Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)

    Background:
    Fascin is a actin cross-linking protein. The Fascin gene contains 5 exons and spans 7 kb. It is a 54-58 kilodalton monomeric actin filament bundling protein originally isolated from sea urchin egg but also found in Drosophila and vertebrates, including humans. Fascin(from the Latin for bundle) is spaced at 11 nanometre intervals along the filament. The bundles in cross section are seen to be hexagonally packed, and the longitudinal spacing is compatible with a model where fascin cross-links at alternating 4 and 5 actins. It is calcium insensitive and monomeric. Fascin binds beta-catenin, and colocalizes with it at the leading edges and borders of epithelial and endothelial cells. The role of Fascin in regulating cytoskeletal structures for the maintenance of cell adhesion, coordinating motility and invasion through interactions with signalling pathways is an active area of research especially from the cancer biology perspective.
    Alternate Names:
    55 kDa actin-bundling protein antibody;Actin bundling protein antibody;actin bundling protein, FAN1 antibody;Fascin 1 antibody;Fascin antibody;Fascin homolog 1 actin bundling protein(Strongylocentrotus purpuratus) antibody;Fascin homolog 1 antibody;Fascin, sea urchin, homolog of, 1 antibody;Fascin1 antibody;FSCN1 antibody.
    Specificity Reaction:Hu,Mo,Rat
    Application Notes:WB: 1:100-500
    Storage :
    Store at –20ºC for one year. Avoid repeated freeze-thaw cycles. At 4ºC for 2-3 weeks after reconstituted.

    This product for research use only, not for use in humans, therapeutic or diagnostic procedures.
    PLlabs公司可供应相应抗体的生物素、辣根过氧化物酶、荧光素(FITC、PE、 CY3、 CY5、 CY7、 PE- CY3/5/7)标记抗体,欢迎大家咨询订购。

    产品细节图片2 产品细节图片3 产品细节图片4
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    图标文献和实验
    相关实验
    • Dendritic Cell-Specific Biolistic Transfection Using the Fascin Gene Promoter

      responses following gene gun-mediated biolistic transfection. Here we report on transcriptional targeting of murine skin DCs using plasmids which include the promoter of the gene of the cytoskeletal protein fascin to control antigen production. Fascin

    • Generation of Antibody Molecules Through Antibody Engineering

      been overcome to a large extent using genetic-engineering techniques to produce chimeric mouse/human and completely human antibodies. Such an approach is particularly suitable because of the domain structure of the antibody molecule ( 2 ), where functional

    • The Antibody Molecule

      The importance of antibody molecules was first recognized in the 1890s, when it was shown that immunity to tetanus and diphtheria was caused by antibodies against the bacterial exotoxins (1 ). Around the same time, it was shown that antisera

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