CDK14 Antibody
Cat#:PL0306517
Isotype:Rabbit Polyclonal IgG
Immunogen:Peptide derived from human CDK14/PFTK1.
Purification: Immunogen affinity purified
Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background:
Serine/threonine-protein kinase involved in the control of the eukaryotic cell cycle, whose activity is controlled by an associated cyclin. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by mediating the phosphorylation of LRP6 at 'Ser-1490', leading to the activation of the Wnt signaling pathway. Acts as a regulator of cell cycle progression and cell proliferation via its interaction with CCDN3. Phosphorylates RB1 in vitro, however the relevance of such result remains to be confirmed in vivo.
Alternate Names:
cdk14; CDK14_HUMAN; Cell division protein kinase 14; Cyclin-dependent kinase 14; hPFTAIRE1; KIAA0834; mKIAA0834; PFTAIRE1; PFTK1; Serine/threonine protein kinase PFTAIRE 1; Serine/threonine-protein kinase PFTAIRE-1.
Specificity Reaction:Hu, Mo, Rat, Chi, Dog, Pig, Cow, Hor,
Application Notes:WB: 1:100-500 E: 1:500-1000 IHC: 1:100-500 IF: 1:50-200
Storage :
Store at –20ºC for one year. Avoid repeated freeze-thaw cycles. At 4ºC for 2-3 weeks after reconstituted.
This product for research use only, not for use in humans, therapeutic or diagnostic procedures.
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