BHLHB9/p60TRP Antibody
Cat#:PL0306257
Isotype:Rabbit Polyclonal IgG
Immunogen:Peptide derived from human BHLHB9/p60TRP.
Purification: Immunogen affinity purified
Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background:
Basic helix-loop-helix (bHLH) proteins are a group of transcription factors that influence the regulation of neurogenesis, cardiogenesis, myogenesis, differentiation and cell proliferation. p60TRP (p60-transcription-regulator-protein), also known as BHLHb9 (basic helix-loop-helix domain containing, class B, 9) or p60-like protein, is a 547 amino acid cytoplasmic and nuclear protein that belongs to the GPRASP family. A few members of the GRASP family are considered G protein-coupled receptors that play a role in many different stimulus-response pathways. Highly expressed in brain, p60TRP may be involved in the control of cellular aging and survival. In colon cancer cells, p60TRP is down regulated due to CpG hypermethylation of its promoter, and patients suffering from Alzheimer disease have low levels of p60TRP.
Alternate Names:
Basic helix loop helix domain containing class B 9; BHLHB 9; bHLHB9; KIAA1701; p60 like protein; p60TRP; Protein BHLHb9; Transcription regulator of 60 kDa; BHLH9_HUMAN .
Specificity Reaction:Hu, Mo, Rat, Dog, Pig, Cow, Hor, Sheep
Application Notes:WB: 1:100-500 E: 1:500-1000 IHC: 1:100-500 IF: 1:100-500 ICC: 1:100-500
Storage :
Store at –20ºC for one year. Avoid repeated freeze-thaw cycles. At 4ºC for 2-3 weeks after reconstituted.
This product for research use only, not for use in humans, therapeutic or diagnostic procedures.
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