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- 文献和实验
- 技术资料
- 保存条件:
-20℃
- 克隆性:
单克隆
- 抗体名:
Tripartite Motif Containing 32 (TRIM32) (C-Term) 抗体
- 规格:
0.1ml/0.2ml
Tripartite Motif Containing 32 (TRIM32)
别名 BBS11, HT2A, LGMD2H, TATIP, 1810045E12Rik, 3f3, Zfp117
抗原表位
其他选择 C-Term
适用
其他选择 小鼠, 大鼠, 犬, 牛, 斑马鱼, 人
宿主
其他选择 兔
克隆类型
多克隆
标记
其他选择 非结合性
应用范围
其他选择 Western Blotting (WB)
Pubmed 找到1个引用
规格 50 μg
发货至 中国 (更改)
发货时间 9至12个工作日
产品编号 yb182403
产品细节 Tripartite Motif Containing 32 (TRIM32) (C-Term) 抗体
免疫原 Synthetic peptide directed towards the C terminal of human TRIM32
序列 GFSIGSVGPD GQLGRQISHF FSENEDFRCI AGMCVDARGD LIVADSSRKE
预测反应 Bovine : 100 %, Chicken : 100 %, Dog : 100 %, Guinea pig : 100 %, Horse : 100 %, Mouse : 100 %, Pig : 100 %, Rabbit : 100 %, Rat : 100 %, Zebrafish : 80 %
产品特性 This is a rabbit polyclonal antibody against TRIM32. It was validated on Western Blot using a cell lysate as a positive control.
纯化方法 Affinity Purified
目标详细情况 Tripartite Motif Containing 32 (TRIM32) (C-Term) 抗体
别名 TRIM32
背景 TRIM32 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. TRIM32 localizes to cytoplasmic bodies. The protein has also been localized to the nucleus, where it interacts with the activation domain of the HIV-1 Tat protein. The Tat protein activates transcription of HIV-1 genes.The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. The protein has also been localized to the nucleus, where it interacts with the activation domain of the HIV-1 Tat protein. The Tat protein activates transcription of HIV-1 genes.The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. The protein has also been localized to the nucleus, where it interacts with the activation domain of the HIV-1 Tat protein. The Tat protein activates transcription of HIV-1 genes.
分子量 72 kDa
基因ID 22954
NCBI登录号 NP_036342, NM_012210
UniProt Q13049
研究领域 Proteolysis / Ubiquitin, Transcription Factors
使用细节 Tripartite Motif Containing 32 (TRIM32) (C-Term) 抗体
应用备注 Optimal working dilutions should be determined experimentally by the investigator.
说明
Antigen size: 653 AA
限制 仅限研究用
贮存及处理 Tripartite Motif Containing 32 (TRIM32) (C-Term) 抗体
状态 Lyophilized
溶解方式 Add 50 µL of distilled water.
浓度 1 mg/mL
缓冲液 PBS buffer with 2 % sucrose
注意事项 Avoid repeated freeze-thaw cycles.
储存条件 -20 °C
储存方法 For longer periods of storage, store at -20 °C
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文献和实验[资源] 所有的看家基因(housekeeping genes)列表+引物设计服务
sapiens serologically defined colon cancer antigen 33 (SDCCAG33), mRNA 1435 NM_007104 Homo sapiens ribosomal protein L10a (RPL10A), mRNA 3006 NM_005762 Homo sapiens tripartite motif-containing 28 (TRIM28 ), mRNA 1473 NM_012138 Homo sapiens
PD-1是55KD的跨膜蛋白,与CD28、ICOS和细胞毒性T淋巴细胞(CTL)相关抗原4(CTLA-4)同属免疫球蛋白超家族成员。其胞外区只有1个IgV样区,与CTLA-4有23%的同源性,但无结合B7-1/B7-2必需的MYPPPY基序;胞浆区有2个酪氨酸残基,尾部有1个ITIM(immunoreceptor tryosine-based inhibitory motif),而无YXXM基序。其他CD28家族中的成员以二硫键连接的同源二聚体形式而存在,而PD-1则以单体形式存在。与CD
所有的看家基因(housekeeping genes)的列表+引物设计服务
10a (RPL10A), mRNA 3006 NM_005762 Homo sapiens tripartite motif-containing 28 (TRIM28), mRNA 1473 NM_012138 Homo sapiens apoptosis antagonizing transcription factor (AATF), mRNA 504 NM_015318
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