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- 详细信息
- 技术资料
- 保存条件：
-20℃
- 克隆性：
单克隆
- 抗体名：
CD38 抗体 (Biotin)
- 规格：
0.1ml/0.2ml
CD38 抗体 (Biotin)抗原
CD38
别名 Cd38-rs1, T10
适用
其他选择 小鼠
宿主
其他选择 大鼠
克隆类型 (克隆位点)
单克隆 (NIMR-5)
标记
其他选择 Biotin
应用范围
其他选择 流式细胞分析技术（FACS）, 免疫沉淀（IP）, 免疫组织化学（IHC）
Pubmed 3个引用可参考
规格 0.5 mg
发货至 中国 (更改)
发货时间 23至28个工作日
产品编号 yb135203
产品细节 CD38 抗体 (Biotin)
克隆位点 NIMR-5
亚型 IgG2a
产品特性 The antibody detects: CD38, Mr 42-46 kDa
目标详细情况CD38 抗体 (Biotin)
背景 Murine CD38, a type II transmembrane glycoprotein, is a bifunctional ectoenzyme capable of catabolizing nicotinamide adenine dinucleotide (NAD+) to cyclic ADP-ribose (cADPR), and then hydrolyzing cADPR to adenosine diphosphoribose (ADPR). It is expressed at high levels on the surface of peripheral B-lineage cells, and at low density on germinal center B cells from unimmunized mice. It has also been reported to be expressed at moderate levels on NK cells, a proportion of peripheral T cells, and a subpopulation of thymocytes which are mostly TCR+, CD4-, CD8-. Murine CD38 is also expressed by all Mac-1+ macrophages in the peritoneal cavities of unimmunized mice, but not by unstimulated bone-marrow-derived macrophages. Monoclonal antibodies to CD38 have been shown to induce B- and T-cell proliferation, protect B cells from apoptosis, and inhibit B lymphopoiesis.
研究领域 CD Antigens, Surface Receptors of Immune Cells
使用细节 CD38 抗体 (Biotin)
应用备注 Working Dilution:
1 µg/10^6 cells
Representative data are included in this product insert.
Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
说明
Induction of B lymphocyte proliferation
样本量 1 mL
限制 仅限研究用
贮存及处理CD38 抗体 (Biotin)
缓冲液 Product is supplied as 0.5 mg in 1.0 mL of PBS / NaN3.
储存液 Sodium azide
注意事项 WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
注意事项 Protect conjugated products from light.
Each reagent is stable for the period shown on the bottle label if stored as directed.
储存条件 4 °C
CD38
别名 Cd38-rs1, T10
适用
其他选择 小鼠
宿主
其他选择 大鼠
克隆类型 (克隆位点)
单克隆 (NIMR-5)
标记
其他选择 Biotin
应用范围
其他选择 流式细胞分析技术（FACS）, 免疫沉淀（IP）, 免疫组织化学（IHC）
Pubmed 3个引用可参考
规格 0.5 mg
发货至 中国 (更改)
发货时间 23至28个工作日
产品编号 yb135203
产品细节 CD38 抗体 (Biotin)
克隆位点 NIMR-5
亚型 IgG2a
产品特性 The antibody detects: CD38, Mr 42-46 kDa
目标详细情况CD38 抗体 (Biotin)
背景 Murine CD38, a type II transmembrane glycoprotein, is a bifunctional ectoenzyme capable of catabolizing nicotinamide adenine dinucleotide (NAD+) to cyclic ADP-ribose (cADPR), and then hydrolyzing cADPR to adenosine diphosphoribose (ADPR). It is expressed at high levels on the surface of peripheral B-lineage cells, and at low density on germinal center B cells from unimmunized mice. It has also been reported to be expressed at moderate levels on NK cells, a proportion of peripheral T cells, and a subpopulation of thymocytes which are mostly TCR+, CD4-, CD8-. Murine CD38 is also expressed by all Mac-1+ macrophages in the peritoneal cavities of unimmunized mice, but not by unstimulated bone-marrow-derived macrophages. Monoclonal antibodies to CD38 have been shown to induce B- and T-cell proliferation, protect B cells from apoptosis, and inhibit B lymphopoiesis.
研究领域 CD Antigens, Surface Receptors of Immune Cells
使用细节 CD38 抗体 (Biotin)
应用备注 Working Dilution:
1 µg/10^6 cells
Representative data are included in this product insert.
Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
说明
Induction of B lymphocyte proliferation
样本量 1 mL
限制 仅限研究用
贮存及处理CD38 抗体 (Biotin)
缓冲液 Product is supplied as 0.5 mg in 1.0 mL of PBS / NaN3.
储存液 Sodium azide
注意事项 WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
注意事项 Protect conjugated products from light.
Each reagent is stable for the period shown on the bottle label if stored as directed.
储存条件 4 °C
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CD38 抗体 (Biotin)
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