Cell Signaling CST 一抗 13172S β

Analysis of -Amyloid Peptide Degradation In Vitro

The accumulation of insoluble Aβ peptide aggregates in the brain is the diagnostic feature of Alzheimer’s disease. Identical deposits are seen in the elderly who are at risk for this disease. The formation of the approx 4 kDa Aβ peptide

Brain报道最新疗法：治疗阿兹海默症，只需光与氧！

的是，由于这些光触媒的激活必须使用可见光，它们的应用也一直被局限在体外。 图片来源：Chem 2 年后，Motomu Kanai 团队再次在 Cell 子刊 Chem 上发表了题为 Near-Infrared Photoactivatable Oxygenation Catalysts of Amyloid Peptide 的研究 [3]， 首次使用近红外光实现了淀粉样蛋白的光氧合，为相关技术的体内使用扫清了障碍，也因此有了这项发表在 Brain 的工作。 图片来源：Chemical Communications

Production and Functional Assays of Recombinant Secreted Amyloid Precursor Protein (APP) (sAPPα)

. The accumulation of amyloid β-peptide (Aβ) in these plaques was the first evidence that APP might be processed abnormally in Alzheimer’s, and this idea was strengthened by the discovery of mutations in APP that segregate with the disease with high penetrance