There are two isoforms of IL22 RA2 produce by alternative splicing. Isoform 1 may play a role in establishing and maintaining successful pregnancy. Isoform 2 is a receptor for IL22. Binds to IL22, prevents interaction with the functional IL-22R complex and blocks the activity of IL22 (in vitro). It may play an important role as an IL22 antagonist in the regulation of inflammatory responses.
IL-22 receptor subunit alpha-2;
IL-22R-alpha-2;
IL-22RA2;
Interleukin-22-binding protein;
IL22BP;
Cytokine receptor family 2 member 10;
CRF2-10;
Cytokine receptor class-II member 10;
Cytokine receptor family type 2, soluble 1;
CRF2-S1;
ZcytoR16