Functions as an interleukin receptor which binds interleukin 12 with low affinity and is involved in IL12 transduction. Associated with IL12RB2 it forms a functional, high affinity receptor for IL12. Associates also with IL23R to form the interleukin 23 receptor which functions in IL23 signal transduction probably through activation of the Jak-Stat signaling cascade
白细胞介素-12受体β1抗体