HDAC6抗体HDAC6兔多抗抗体Protein phosp
hatase 1 regulatory subunit 90 antibody抗体HDAC6 Antibody抗体- ￥440 - 1320
- CUSABIO
- CN
- CSB-PA010242ESR1HU
- 2025年07月16日
- ELISA, IHC; Recommended dilution: IHC:1:20-1:200
- Rabbit
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Recombinant Human Histone deacetylase 6 protein (160-470AA)
- 亚型：
IgG
- 形态：
Liquid
- 保存条件：
Upon receipt, store at -20℃ or -80℃. Avoid repeated freeze.
- 克隆性：
Polyclonal
- 标记物：
Non-conjugated
- 适应物种：
Human
- 保质期：
6个月
- 抗原来源：
Homo sapiens (Human)
- 目录编号：
Q9UBN7
- 级别：
优
- 库存：
200
- 供应商：
武汉华美生物工程有限公司
- 宿主：
Rabbit
- 应用范围：
ELISA, IHC; Recommended dilution: IHC:1:20-1:200
- 浓度：
>95%,Antigen Affinity Purified
- 靶点：
HDAC6
- 抗体英文名：
HDAC6 Antibody
- 抗体名：
Protein phosphatase 1 regulatory subunit 90 antibody
- 规格：
100μl/50μl/20μl
| 规格： | 100μl | 产品价格： | ￥1320.0 |
|---|---|---|---|
| 规格： | 50μl | 产品价格： | ￥880.0 |
| 规格： | 20μl | 产品价格： | ￥440.0 |
保存缓冲液
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.功能
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer. In addition to its protein deacetylase activity, plays a key role in the degradation of misfolded proteins: when misfolded proteins are too abundant to be degraded by the chaperone refolding system and the ubiquitin-proteasome, mediates the transport of misfolded proteins to a cytoplasmic juxtanuclear structure called aggresome. Probably acts as an adapter that recognizes polyubiquitinated misfolded proteins and target them to the aggresome, facilitating their clearance by autophagy.风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验Two-hybrid analysis of genetic regulatory networks
. (1993). The retinoblastoma protein associates with the protein phophatase type 1 catalytic subunit. Genes and Dev. 7 , 555-569. Estojak, J., Brent, R., and Golemis, E. A. (1995). Correlation of two-hybrid affinity data with in vitro measurements
labeled• labeled secondary antibody or more complex detection system.• secondary antibody against the immunoglobulins of the primary antibody source减少或消除非特异性染色的方法• 最常见原因 蛋白吸附于高电荷的胶原和结缔组织成分上• 最有效方法1. 在用第一抗体前加制备第二抗体动物之非免疫血清（1:5-20）10-20min，2. 加入2-5%牛血清白蛋白可进
may be directly labeled• labeled secondary antibody or more complex detection system.• secondary antibody against the immunoglobulins of the primary antibody source减少或消除非特异性染色的方法• 最常见原因 蛋白吸附于高电荷的胶原和结缔组织成分上• 最有效方法1. 在用第一抗体前加制备第二抗体动物之非免疫血清（1:5-20）10-20min，2. 加入2-5
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