- ￥968 - 4954
- MedChemExpress(MCE)
- 美国
- HY-15714
- 2025年12月05日
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
1449236-96-7
- 规格：
10 mM * 1 mL/1 mg/2 mg/5 mg/10 mg/25 mg
| 规格： | 10 mM * 1 mL | 产品价格： | ￥2693.0 |
|---|---|---|---|
| 规格： | 1 mg | 产品价格： | ￥968.0 |
| 规格： | 2 mg | 产品价格： | ￥1400.0 |
| 规格： | 5 mg | 产品价格： | ￥2163.0 |
| 规格： | 10 mg | 产品价格： | ￥3113.0 |
| 规格： | 25 mg | 产品价格： | ￥4954.0 |
MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务。
NMS-859
CAS No. : 1449236-96-7
MCE 国际站：NMS-859
产品活性：NMS-859 是一种有效的，共价的 VCP (p97) 抑制剂，细胞中分别在 60 μM 和 1 mM ATP 的条件下，对野生型 VCP 的 IC50 值分别为 0.37 和 0.36 μM。
研究领域：Cell Cycle/DNA Damage
作用靶点：p97
In Vitro: NMS-859 is a potent VCP inhibitor, with IC50s of 0.37 and 0.36 μM for wild-type VCP in the presence of 60 μM and 1 mM ATP in cells, respectively. NMS-859 shows very weak inhibitory activity against VCPC522T. NMS-859 also suppresses the proliferation of cells, with IC50s of 3.5 μM and 3.0 μM in HCT116 and HeLa cell lines, respectively.
相关产品：Covalent Screening Library Plus | Bioactive Compound Library Plus | Cell Cycle/DNA Damage Compound Library | Anti-Cancer Compound Library | Antiviral Compound Library | Anti-Aging Compound Library | Covalent Screening Library | Ubiquitination Compound Library | Endoplasmic Reticulum Stress Compound Library | Membrane Protein-targeted Compound Library | Cysteine Targeted Covalent Library | CB-5083 | NMS-873 | Eeyarestatin I | DBeQ | MSC1094308 | ML240 | CB-5339 | ML241 hydrochloride | UPCDC-30245 | NW 1028 | UPCDC30766 | VCP/p97 inhibitor-1
热门产品线：重组蛋白 | 化合物库 | 天然产物 | 荧光染料 | PROTAC | 同位素标记物
Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Dye Reagents | PROTAC | Isotope-Labeled Compounds
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验Basic Protocol 3: Determination of the Observed Association Rate (kob) of the Radiolabel Basic Protocol 4: Competition Kinetics Between [3H]NMS and Unlabeled Ligands Support Protocol
Practical Aspects of Radioligand Binding
Figure 1.3.1 Saturation binding to muscarinic receptors on N1E‐115 mouse neuroblastoma cells. Six concentrations of [3 H] N ‐methylscopolamine ([3 H]NMS), with or without 10 µM unlabeled NMS, were incubated
907.2 1,814.4 2,000 0.05 0.04921 0.0551 1 0.9842 0.8267 50 100 110.23 0.0508 0.05 0.056 1.016 1 0.8402 50.8 101.6 112 0.0605 0.05954 0.0667 1.21 1.19 1 60.48 120.96 133
技术资料暂无技术资料 索取技术资料
