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文献和实验The Importance of Mouse ES Cell Line Selection
The choice of a specific parental ES cell line used to create a genetically modified mouse has critical impact on the overall success of the project – affecting costs, complexity of effort, and time to efficient project completion
In Vivo Germ Line Stem Cell Migration: A Mouse Model
A stem cell niche is a specialized tissue environment that controls the proliferation and differentiation of its resident stem cells. The functions of these structures have been well characterized in adult organisms. In particular, the bone
Microglia Isolation from Adult Mouse Brain
Although microglia isolation from embryonic or postnatal mouse brain is possible using a number of different protocols, microglia isolation from adult brain is more challenging and often results in low yields. Here, we describe a protocol
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