单核细胞趋化蛋白1抗体(人)

单核细胞趋化蛋白1抗体(人)产品标准

浓缩液(1mg/1ml) 亲和纯化抗体

产品应用

WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500 （石蜡切片需做抗原修复）

单核细胞趋化蛋白1抗体(人)产品介绍

生长因子和激素（ Growth Factor and Hormones）

巨噬细胞趋化蛋白1(MCP1)具有多向性调节作用的核转录因子，它可诱导与免疫和炎症有关的多种基因转录.MCP-1免疫组化阳性信号主要位于胞浆内.分子量为12～25KDa

&nbs;Chemotactic factor that attracts monocytes and basophils but not neutrophils or eosinophils. Augments monocyte anti-tumor activity. Has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. Monomer or homodimer; in equilibrium. Binds to CCR2 and CCR4. Is tethered on endothelial cells by glycosaminoglycan (GAG) side chains of proteoglycans. Processing at the N-terminus can regulate receptor and targetcell selectivity. Deletion of the N-terminal residue converts it from an activator of basophil to an eosinophil chemoattractant. Genetic variations in CCL2 determine Mycobacterium tuberculosis susceptibility Belongs to the intercrine beta (chemokine CC) family. The MCP-1( the monocyte chemotactic protein1) has many pits that regulates the function toward sex to turn to record the factor, it can induce to have relation with inflammation with the immunity various genes turn to record.The immunity MCP-1 set turns the male signal to mainly locate the afterbirth syrup inside.
&nbs;mol wt:11kDa
Other Aliases:
monocyte chemotactic protein 1; CCL 2; CCL2; Chemokine C C motif ligand 2; Chemokine CC Motif Ligand 2; GDCF 2; GDCF 2 HC11; GDCF2; HC11; HSMCR30; JE; MCAF; MCP 1; MGC9434; Monocyte chemoattractant protein 1; Monocyte chemotactic and activating factor; Monocyte chemotactic protein 1; Monocyte secretory protein JE; SCYA2; Small inducible cytokine A2; Small inducible cytokine subfamily A Cys Cys member 2; SMC CF; SMCCF
单核细胞趋化蛋白1抗体(人)