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文献和实验【信息】The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling
molecule) are recruited to TIR (Toll/interleukin-1 (IL-1) receptor) domains to initiate signalling, whereas SARM (sterile - and armadillo-motif-containing protein) inhibits TRIF-dependent signalling. MyD88 is the universal adaptor used by all TLRs
Overview of Receptor Allosterism
), a potent, orally bioavailable, and selective small‐molecule inhibitor of chemokine receptor CCR5 with broad‐spectrum anti‐human immunodeficiency virus type 1 activity. Antimicrob. Agents Chemother. 49:4721‐4732.
Characterization of Nuclear Receptor Ligands by Multiplexed Peptide Interactions
., and McDonnell, D.P. 1999. Peptide antagonists of the human estrogen receptor. Science 285:744‐746. Northrop, J.P., Nguyen, D., Piplani, S., Olivan, S.E., Kwan, S.T., Go, N.F., Hart, C
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