凝血调节蛋白抗体

凝血调节蛋白抗体产品标准

浓缩液(1mg/1ml) 亲和纯化抗体

产品应用

WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500 （石蜡切片需做抗原修复）

凝血调节蛋白抗体产品介绍

CD141是一种转膜糖蛋白，表达于许多正常组织中如动、静脉内皮细胞，以及间皮细胞.
CD141/Thrombomodulin is an exclusively endothelial cell surface glycoprotein that forms a 1:1 complex with thrombin. Binding of thrombin to this high-affinity receptor alters its specificity toward several substrates. The complex activates protein C approximately 1000 times faster than thrombin alone. Activated protein C degrades clotting factors V and VIII; thus, thrombomodulin converts thrombin into a physiologic anticoagulant. Thrombomodulin is also found in the circulatory and urinary systems, the physiologic significance of this is obscure.
Also known as:
T hrombomodulin; CD 141; CD141; CD141 antigen; Fetomodulin; THBD; THRM; TM