- 询价
- PeproTech
- AF-300-08-5
- 美国
- 2025年10月21日
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- 详细信息
- 技术资料
- 库存：
大量
- 供应商：
Peprotech(派普泰克)
- 英文名：
Recombinant Human MIP-1α (CCL3)
Recombinant Human MIP-1α (CCL3)
Catalog Number:
AF-300-08
Synonyms:
Macrophage Inflammatory Protein-1α, CCL3,LD78α
Description:
Both MIP-1α and MIP-1β are structurally and functionally related CC chemokines. They participate in host response to invading bacterial, viral, parasite and fungal pathogens, by regulating the trafficking, and activation state, of selected subgroups of inflammatory cells (e.g. macrophages, lymphocytes and NK cells). While both MIP-1α and MIP-1β exert similar effects on monocytes, their effect on lymphocytes differ; with MIP-1α selectively attracting CD8+ lymphocytes, and MIP-1β selectively attracting CD4+ lymphocytes. Additionally, MIP-1α and MIP-1β have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. Both human and murine MIP-1α and MIP-1β are active on human and murine hematopoietic cells. Recombinant Human MIP-1α is a 7.8 kDa protein containing 70 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines. Manufactured using all Animal-Free reagents.
AA Sequence:
ASLAADTPTA CCFSYTSRQI PQNFIADYFE TSSQCSKPGV IFLTKRSRQV CADPSEEWVQ KYVSDLELSA
Source:
E.coli
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Biological Activity:
Determined by its ability to chemoattract human monocytes using a concentration range of 1.0-10.0 ng/ml.
Research Interests:
Country of Origin:
USA
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PeproTech重组人MIP-1α(CCL3)(无动物成分) 5ug
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