The cripto gene is expressed both in ES cells and during the early phases of embryo development, while in adults it is reactivated in a wide range of epithelial cancers. It could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm.
mol wt:21kDa
Other Aliases: Teratocarcinoma-derived growth factor 1 ; TDGF1; CR; CRGF; CRIPTO;Cripto-1