细胞凋亡信号调节激酶1/丝裂原活化蛋白激酶激酶激酶5抗体

细胞凋亡信号调节激酶1/丝裂原活化蛋白激酶激酶激酶5抗体产品标准

浓缩液(1mg/1ml) 亲和纯化抗体

产品应用

WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500 （石蜡切片需做抗原修复）

细胞凋亡信号调节激酶1/丝裂原活化蛋白激酶激酶激酶5抗体产品介绍

Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK. The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells. MAPKKK5 contains 1,374 amino acids with all 11 kinase subdomains. Northern blot analysis shows that MAPKKK5 transcript is abundantly expressed in human heart and pancreas. The MAPKKK5 protein phosphorylates and activates MKK4 (aliases SERK1, MAPKK4) in vitro, and activates c-Jun N-terminal kinase (JNK)/stress-activated protein kinase (SAPK) during transient expression in COS and 293 cells; MAPKKK5 does not activate MAPK/ERK.
Also known as Mitogen-activated protein kinase kinase kinase 5; MAPK/ERK kinase kinase 5; MEK kinase 5; MEKK 5; Apoptosis signal-regulating kinase 1; ASK-1; MAP3K5; ASK1; MAPKKK5; MEKK5

细胞凋亡信号调节激酶1/丝裂原活化蛋白激酶激酶激酶5抗体其它产品：yb-12516R Arginyl tRNA synthetase精氨酰tRNA合成酶抗体
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yb-12955R phospho-Acetyl Coenzyme A Carboxylase alpha (Ser1263)磷酸化乙酰辅酶A羧化酶抗体
yb-12956R phospho-ABCA1 (Ser2054)磷酸化腺苷三磷酸结合盒转运体A1抗体
yb-12957R phospho-Aconitase 1 (Ser138)磷酸化铁调节蛋白1抗体
yb-12958R phospho-Aconitase 1 (Ser711)磷酸化铁调节蛋白1抗体
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