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Bag3/Bag3蛋白Recombinant Mouse B

AG family molecular chaperone regulator 3 (Bag3)重组蛋白Bcl-2-associated athanogene 3Bcl-2-binding protein Bis蛋白
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  • ¥1836 - 14844
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  • CSB-YP864372MO
  • 2025年07月07日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件

      Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

    • 保质期

      Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.

    • 英文名

      Recombinant Mouse BAG family molecular chaperone regulator 3 (Bag3)

    • 库存

      200

    • 供应商

      武汉华美生物工程有限公司

    • 规格

      1mg/100μg/20μg

    规格:1mg产品价格:¥14844.0
    规格:100μg产品价格:¥3456.0
    规格:20μg产品价格:¥1836.0

    纯度:

    Greater than 90% as determined by SDS-PAGE.

    基因名:

    Bag3

    Uniprot No.:

    Q9JLV1

    别名:

    Bcl-2-associated athanogene 3Bcl-2-binding protein Bis

    种属:

    Mus musculus (Mouse)

    蛋白长度:

    Full Length of Mature Protein

    来源:

    Yeast

    分子量:

    63.7 kDa

    表达区域:

    2-577aa

    氨基酸序列:

    SAATQSPMMQMASGNGASDRDPLPPGWEIKIDPQTGWPFFVDHNSRTTTWNDPRVPPEGPKDTASSANGPSRDGSRLLPIREGHPIYPQLRPGYIPIPVLHEGSENRQPHLFHAYSQPGVQRFRTEAAAATPQRSQSPLRGGMTEAAQTDKQCGQMPATATTAAAQPPTAHGPERSQSPAASDCSSSSSSASLPSSGRSSLGSHQLPRGYIPIPVIHEQNITRPAAQPSFHQAQKTHYPAQQGEYQPQQPVYHKIQGDDWEPRPLRAASPFRSPVRGASSREGSPARSGTPVHCPSPIRVHTVVDRPQPMTHREPPPVTQPENKPESKPGPAGPDLPPGHIPIQVIRREADSKPVSQKSPPPAEKVEVKVSSAPIPCPSPSPAPSAVPSPPKNVAAEQKAAPSPAPAEPAAPKSGEAETPPKHPGVLKVEAILEKVQGLEQAVDSFEGKKTDKKYLMIEEYLTKELLALDSVDPEGRADVRQARRDGVRKVQTILEKLEQKAIDVPGQVQVYELQPSNLEAEQPLQEIMGAVVADKDKKGPENKDPQTESQQLEAKAATPPNPSNPADSAGNLVAP

    蛋白标签:

    N-terminal 6xHis-tagged

    产品提供形式:

    Liquid or Lyophilized powder

    缓冲液:

    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

    货期:

    3-7 business days

    注意事项:

    Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.

    功能:

    Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release. Has anti-apoptotic activity.

    内毒素:

    Not test.

    SDS-PAGE:

    (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

    LC-MS Image Description/Western Blot:

    /

    Product types:

    In Stock Protein

    Biological_Activity:

    /

    Research Areas:

    Others

    Reconstitution:

    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

    Reference:

    Bis, a Bcl-2-binding protein that synergizes with Bcl-2 in preventing cell death.Lee J.H., Takahashi T., Yasuhara N., Inazawa J., Kamada S., Tsujimoto Y.Oncogene 18:6183-6190(1999)

    Function:

    Co-chaperone for HSP70 and HSC70 chaperone proteins. Acts as a nucleotide-exchange factor (NEF) promoting the release of ADP from the HSP70 and HSC70 proteins thereby triggering client/substrate protein release. Nucleotide release is mediated via its binding to the nucleotide-binding domain (NBD) of HSPA8/HSC70 where as the substrate release is mediated via its binding to the substrate-binding domain (SBD) of HSPA8/HSC70. Has anti-apoptotic activity. Plays a role in the HSF1 nucleocytoplasmic transport.

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    图标文献和实验
    该产品被引用文献
    Bis, a Bcl-2-binding protein that synergizes with Bcl-2 in preventing cell death.Lee J.H., Takahashi T., Yasuhara N., Inazawa J., Kamada S., Tsujimoto Y.Oncogene 18:6183-6190(1999)
    相关实验
    • 参考文献

      , 2001,28(3): 415 [38] 王京兰, 万晶宏, 罗凌,等. 蛋白质组研究中肽质量指纹谱鉴定方法的建立及应用. 生物化学与生物物理学报, 2000,32: 373-378 [39] Guo X, Ying W, Wan J, et al. Proteomic characterization of early stage differentiation of mouse embryonic stem cells into neural cells induced

    • 分子生物学常用名词解释中英文对照

      的有限区域。 Allele(等位基因):在染色体上占据给定位点基因的不同形式。 Allelic exclusion(等位基因排斥):形容在特殊淋巴细胞中只有一个等位基因来表达编码的免疫球蛋白质。 Allosteric control(别构调控):指蛋白质一个位点上的反应能够影响另一个位点活性的能力。 Alu-equivalent family(Alu 相当序列基因):哺乳动物基因组上一组序列,它们与人类Alu家族相关。 Alu family (Alu家族):人类基因组中一系列分散

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    文献支持
    Bag3/Bag3蛋白Recombinant Mouse BAG family molecular chaperone regulator 3 (Bag3)重组蛋白Bcl-2-associated athanogene 3Bcl-2-binding protein Bis蛋白
    ¥1836 - 14844