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Il18/Il18蛋白Recombinant Rat Int

erleukin-18 (Il18)重组蛋白Interferon gamma-inducing factor ;IFN-gamma-inducing factorInterleukin-1 gamma ;IL-1 gamma蛋白
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  • ¥1836 - 14796
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  • CN
  • CSB-RP176194r
  • 2025年07月10日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件

      Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

    • 保质期

      Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.

    • 英文名

      Recombinant Rat Interleukin-18 (Il18)

    • 库存

      200

    • 供应商

      武汉华美生物工程有限公司

    • 规格

      1mg/100μg/20μg

    规格:1mg产品价格:¥14796.0
    规格:100μg产品价格:¥3468.0
    规格:20μg产品价格:¥1836.0

    纯度:

    Greater than 90% as determined by SDS-PAGE.

    基因名:

    Il18

    Uniprot No.:

    P97636

    别名:

    Interferon gamma-inducing factor ;IFN-gamma-inducing factorInterleukin-1 gamma ;IL-1 gamma

    种属:

    Rattus norvegicus (Rat)

    蛋白长度:

    Full Length of Mature Protein

    来源:

    E.coli

    分子量:

    22.3 kDa

    表达区域:

    37-194aa

    氨基酸序列:

    HFGRLHCTTAVIRSINDQVLFVDKRN_P_PVFEDMPDIDRTANESQTRLIIYMYKDSEVRGLAVTLSVKDGRMSTLSCKNKIISFEEMN_P_PENIDDIKSDLIFFQKRVPGHNKMEFESSLYEGHFLACQKEDDAFKLVLKRKDENGDKSVMFTLTNLHQS

    蛋白标签:

    N-terminal 6xHis-tagged

    产品提供形式:

    Liquid or Lyophilized powder

    缓冲液:

    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

    货期:

    13-23 business days

    注意事项:

    Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.

    功能:

    Augments natural killer cell activity in spleen cells and stimulates interferon gamma production in T-helper type I cells.

    内毒素:

    Not test.

    SDS-PAGE:

    (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

    LC-MS Image Description/Western Blot:

    /

    Product types:

    Developed Protein

    Biological_Activity:

    /

    Research Areas:

    Others

    Reconstitution:

    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

    Reference:

    Cloning of the cDNA for interleukin-18 in PC12 and expression in Escherichia coli.Kim S.-J., Kim C.-S., Song K.-Y., Kim J.-S., Jung K.-S. IL-18 translational inhibition restricts IFN-gamma expression in crescentic glomerulonephritis.Garcia G.E., Xia Y., Ku G., Johnson R.J., Wilson C.B., Feng L.Kidney Int. 64:160-169(2003)

    Function:

    Augments natural killer cell activity in spleen cells and stimulates interferon gamma production in T-helper type I cells.

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    图标文献和实验
    该产品被引用文献
    Cloning of the cDNA for interleukin-18 in PC12 and expression in Escherichia coli.Kim S.-J., Kim C.-S., Song K.-Y., Kim J.-S., Jung K.-S. IL-18 translational inhibition restricts IFN-gamma expression in crescentic glomerulonephritis.Garcia G.E., Xia Y., Ku G., Johnson R.J., Wilson C.B., Feng L.Kidney Int. 64:160-169(2003)
    相关实验
    • 白介素18信号通路图

      相关专题   &NBS p; Interleukin 18 (interferon-gamma-inducing factor) IL-18 is a cytokine that belongs to the IL-1 superfamily and is produced by macrophages and other Cell s. IL-18 works by binding

    • 【请教】用哪个免疫基因芯片好?

      -Class (D200-domain) Cytokine Receptor Activity (19): CSF2RB, CSF3R, IFNAR2, IL10RA, IL10RB, IL12B, IL12RB1, IL12RB2, IL13RA1, IL20RA, IL2RB, IL3RA, IL4R, IL5RA, IL6R, IL6ST, IL7R, IL9R, LIFR. Interleukin Receptors (8): IL12RB1, IL12RB2, IL15RA, IL18

    • 「魔高一尺道高一丈」周挺等 Nature 报道分泌型免疫检查点,伪 IL-18 肿瘤免疫治疗异军突起

      . Ring 课题组周挺博士以第一作者在 Nature 上在线发表了题为 IL-18BP is a secreted immune checkpoint and barrier to IL-18 immunotherapy 的研究成果。该研究发现肿瘤微环境中产生的 IL-18 结合蛋白(IL-18BP)可能充当「分泌型免疫检查点」限制了 IL-18 免疫治疗的效果;作者通过定向进化的方法筛选得到了一种可维持信号转导能力,但不会被 IL-18BP 抑制的 IL-18(decoy-resistant IL

    图标技术资料

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    Il18/Il18蛋白Recombinant Rat Interleukin-18 (Il18)重组蛋白Interferon gamma-inducing factor ;IFN-gamma-inducing factorInterleukin-1 gamma ;IL-1 gamma蛋白
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