CLEC7A / Dectin-1抗体

CLEC7A / Dectin-1抗体产品信息

免疫原 :
Recombinant mouse CLEC7A protein ( Catalog#50233-M07H )
Antibody Type : Rabbit Polyclonal Antibody ( Antibody Purification Platform )
抗体宿主 :
Rabbit IgG
缓冲液 : 0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.
制备方法 :
Produced in rabbits immunized with purified, human cell-derived, recombinant mouse CLEC7A ( rM CLEC7A ; Catalog#50233-M07H ; NP_064392.2 ; Phe 69 - Leu 244 ). CLEC7A specific IgG was purified by mouse CLEC7A affinity chromatography.
CLEC7A / Dectin-1抗体背景综述
Mouse C-type lectin domain family 7 member A, also known as Dendritic cell-associated C-type lectin 1, Dectin-1, Beta-glucan receptor, C-type lectin superfamily member 12, BGR, CLECSF12, and CLEC7A, is a single-pass type II membrane protein which contains one C-type lectin domain. CLEC7A (Dectin-1) belongs to the large family of pattern recognition receptors (PRRs) which recognize conserved pathogen-associated molecular patterns (PAMPs). CLEC7A (Dectin-1) is highly expressed in peripheral blood leukocytes and dendritic cells. It is also detected in spleen, bone marrow, lung, muscle, stomach and placenta. CLEC7A (Dectin-1) is a pattern-recognition receptor that predominantly recognizes beta-glucans from fungi, plants and bacteria. CLEC7A (Dectin-1) is implicated in immunological defenses against pathogens that have beta-glucans. CLEC7A (Dectin-1) was identified as the most important receptor for beta-glucan. Recognition of beta-glucan by CLEC7A (Dectin-1) triggers effective immune response, including phagocytosis and proinflammatory factor production, to eliminate infecting fungi. CLEC7A (Dectin-1) is also involved in the adaptive immune response as well as autoimmune diseases and immune tolerance. CLEC7A (Dectin-1) is a small C-type lectin receptor for fungal cell wall beta-glucan. Its homologues in some species, including mouse and human. The sequence of mouse CLEC7A (Dectin-1) is found to be highly homologous to that of the rat. It possesses essential motifs for the recognition of beta-glucan and signal transduction. Mouse CLEC7A (Dectin-1) plays essential roles in immune responses against fungi.
CLEC7A / Dectin-1抗体相关产品如下：
hz-0366Rs Rabbit Anti-FITC Whole serum兔抗荧光素抗血清
hz-0302Rs Rabbit anti-HRP whole serum兔抗HRP抗血清
hz-0360Rs Rabbit anti-human IgA whole serum兔抗人IgA抗血清
hzA-8s Rabbit anti-human Kappa Chain whole serum兔抗人Kappa链抗血清（k-链抗血清）
hz-0411Rs Rabbit anti-human IgG heavy chain constant region whole serum兔抗人IgG（γ-链）恒定区抗血清
hz-0292Rs BSA牛血清白蛋白抗血清
hz-0295hz-hzy7 Rabbit IgG/Cy7荧光素Cy7标记兔IgG(细胞流式同型对照)
hz-0296hz-hzy7 Mouse IgG/Cy7荧光素Cy7标记小鼠IgG(细胞流式同型对照)
hz-0294hz-hzy7 Goat IgG/Cy7荧光素Cy7标记羊IgG(细胞流式同型对照)
hz-0293hz-hzy7 Rat IgG/Cy7荧光素Cy7标记大鼠IgG(细胞流式同型对照)
hz-0295hz-A555 Rabbit IgG/Alexa Fluor 555Alexa Fluor 555标记兔IgG(细胞流式同型对照)
hz-0366R-hzE Rb Anti-FITC/PE荧光素PE标记兔抗FITC
hz-0360G-hzE Goat Anti-human IgA/PE荧光素PE标记羊抗人IgA
hz-0312hz-hzE Avidin/PE荧光素PE标记亲合素
hz-0362hz-hzE Protein A/PEPE标记蛋白A
hz-0296hz-hzE Mouse IgG/PE荧光素PE标记小鼠IgG(细胞流式同型对照)
hz-0294hz-hzE Goat IgG/PE荧光素PE标记羊IgG(细胞流式同型对照)
hz-0293hz-hzE Rat IgG/PE荧光素PE标记大鼠IgG(细胞流式同型对照)
hz-0326hz-hzE Bovine IgG/PE荧光素PE标记牛IgG
hz-0327hz-hzE Bovine IgM/PE荧光素PE标记牛IgM
hz-0310hz-hzE Chicken IgG/PE荧光素PE标记鸡IgG
hz-0314hz-hzE Chicken IgM/PE荧光素PE标记鸡IgM
hz-0373hz-hzE dog IgM/PE荧光素PE标记狗IgM
hz-0370hz-hzE Goat IgM/PE荧光素PE标记羊IgM
hz-0358hz-hzE Guinea IgG/PE荧光素PE标记豚鼠IgG
hz-0375hz-hzE Guinea IgM/PE荧光素PE标记豚鼠IgM
hz-0308hz-hzE Horse IgG/PE荧光素PE标记马IgG
hz-0374hz-hzE Horse IgM/PE荧光素PE标记马IgM
hz-0297hz-hzE human IgG/PE荧光素PE标记人IgG
hz-0345hz-hzE human IgM/PE荧光素PE标记人IgM
hz-0360hz-hzE human IgA/PE荧光素PE标记人IgA
hz-0335hz-hzE Monkey IgG/PE荧光素PE标记猴IgG
hz-0336hz-hzE Monkey IgM/PE荧光素PE标记猴IgM
hz-0368hz-hzE Mouse IgM/PE荧光素PE标记小鼠IgM
hz-0309hz-hzE pig IgG/PE荧光素PE标记猪IgG
hz-0777hz-hzE Mink IgG/PE荧光素PE标记水貂IgG
hz-0369hz-hzE Rabbit IgM/PE荧光素PE标记兔IgM
hz-0346hz-hzE Rat IgM/PE荧光素PE标记大鼠IgM
hz-0884hz-hzE rHIL-1Ra/PE荧光素PE标记重组人白介素-1受体拮抗剂
hz-0789hz-hzE Insulin/PE荧光素PE标记猪胰岛素蛋白
hz-hz0002-hzE KLH/PE荧光素PE标记血蓝蛋白
hz-0945hz-hzE Albumin /PE荧光素PE标记人血白蛋白
hz-2179hz-hzE AACT/PE荧光素PE标记胰糜蛋白酶