CD48 / BCM1 / SLAMF2抗体

CD48 / BCM1 / SLAMF2抗体产品信息

免疫原 :
Recombinant mouse CD48 protein ( Catalog # 50415-M08H )
Antibody Type : Rabbit Polyclonal Antibody ( Antibody Purification Platform )
抗体宿主 :
Rabbit IgG
缓冲液 : 0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.
制备方法 :
Produced in rabbits immunized with purified, human cell-derived, recombinant mouse CD48 ( rM CD48 ; Catalog#50415-M08H ; Met 1 - Arg 216 ; NP_031675.1 ). CD48 specific IgG was purified by mouse CD48 affinity chromatography
CD48 / BCM1 / SLAMF2抗体背景综述
Mouse CD48, also known as SLAMF2, BCM-1 and BLAST-1, is a GPI-linked protein belonging to the CD2 subfamily of immunoglobulin superfamily molecules. CD48 is expressed on most lineage-committed hematopoietic cells but not on hematopoietic stem cells or multipotent hematopoietic progenitors. CD48 has a striking array of biological functions, among them adhesion, pathogen recognition, cellular activation, and cytokine regulation. CD48 performs biological functions in a variety processes including adhesion, pathogen recognition, cellular activation, and cytokine regulation, and emerges as a critical effector molecule in immune responses. In rodents, CD48 is the ligand for CD2 whereas in humans, CD58 is the ligand for CD2. CD48 has a high degree of sequence homology to CD58 (LFA-3), and Mouse CD48 shares approximately 50% aa sequence identity with human CD48
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