Fucosyltransferase-10 / FUT10抗

Fucosyltransferase-10 / FUT10抗体产品信息

免疫原 :
Recombinant human FUT10 protein ( Catalog#11327-H07H )
Antibody Type : Rabbit Polyclonal Antibody ( Antibody Purification Platform )
抗体宿主 :
Rabbit IgG
缓冲液 : 0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.
制备方法 :
Produced in rabbits immunized with purified, human cell-derived, recombinant human FUT10 ( rh FUT10 ; Catalog#11327-H07H ; Q6P4F1-1 ; Leu 32 - Asp 479 ). FUT10 specific IgG was purified by human FUT10 affinity chromatography
Fucosyltransferase-10 / FUT10抗体背景综述
Human Alpha-(1,3)-fucosyltransferase 10, also known as Galactoside 3-L-fucosyltransferase 10, Fucosyltransferase 10, Fucosyltransferase X, Fuc-TX, and FUT10, is single-pass type I I membrane protein which belongs to the glycosyltransferase 10 family. Fucosyltransferases are the enzymes transferring fucose from GDP-Fuc to Gal in an alpha1,2-linkage and to GlcNAc in alpha1,3-linkage, alpha1,4-linkage, or alpha1,6-linkage. All fucosyltransferases utilize the same nucleotide sugar, their specificity reside in the recognition of the acceptor and in the type of linkage formed. Fucosyltransferases share some common structural and catalytic features. On the basis of protein sequence similarities, these enzymes can be classified into four distinct families: (1) the alpha-2-fucosyltransferases, (2) the alpha-3-fucosyltransferases, (3) the mammalian alpha-6-fucosyltransferases, and (4) the bacterial alpha-6-fucosyltransferases. The alpha-3-fucosyltransferases constitute a distinct family as they lack the consensus peptide, but some regions display similarities with the alpha-2 and alpha-6-fucosyltranferases
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