HPRG / HRG抗体

HPRG / HRG抗体产品信息

免疫原 :
Recombinant human HPRG protein ( Catalog#10836-H08H )
抗体类型: Rabbit Monoclonal Antibody ( Rabbit mAb Service Platform )
克隆号 :
28
抗体宿主 :
Rabbit IgG
缓冲液 : 0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.
制备方法 :
This antibody was obtained from a rabbit immunized with purified, human cell-derived, recombinant human HPRG ( rhHPRG; Catalog#10836-H08H; Met 1-Lys 525; NP_000403.1 ).
HPRG / HRG抗体背景综述
Histidine-rich glycoprotein, also known as HRG and HPRG, is a glycoprotein located in plasma and platelets, and contains an unusually large amount of histidine and proline. In human, five distinct domains are recognized in the mature HPRG molecule. The specific functions of HRG remain unclear, but it is known that the protein binds heme, dyes and divalent metal ions. It inhibits rosette formation and interacts with heparin, thrombospondin and plasminogen. Two of the protein's effects, the inhibition of fibrinolysis and the reduction of inhibition of coagulation, indicate a potential prothrombotic effect.
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