免疫原 :
Recombinant Human RET protein (Catalog#11997-H08H1)
Antibody Type : Rabbit Monoclonal Antibody ( Rabbit mAb Service Platform )
克隆号 :
009
抗体宿主 :
Rabbit IgG
缓冲液 : 0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.
制备方法 :
This antibody was obtained from a rabbit immunized with purified, recombinant Human RET (rh RET; Catalog#11997-H08H1; P07949-1; Met1-Arg635).
RET抗体 Background
Proto-oncogene tyrosine-protein kinase receptor Ret, also known as Cadherin family member 12, Proto-oncogene c-Ret, RET and CDHF12, is a single-pass type I membrane protein which belongs to theprotein kinase superfamily and Tyr protein kinase family. RET / CDHF12 is a probable receptor with tyrosine-protein kinase activity. It is important for development. RET / CDHF12 contains onecadherin domain and oneprotein kinase domain. RET / CDHF12 can activate various signaling pathways such as RAS/extracellular signal-regulated kinase (ERK), phosphatidylinositol 3-kinase (PI3K)/AKT, p38 mitogen-activated protein kinase (MAPK) and c-Jun N-terminal kinase (JNK) pathways. These signaling pathways are activated via binding of adaptor proteins to intracellular tyrosine residues of RET phosphorylated by its own kinase activity. The RET is profoundly involved in the development of several human neuroendocrine diseases. Defects in RET may be a cause of colorectal cancer, Hirschsprung disease type 1 (HSCR1), medullary thyroid carcinoma (MTC), multiple neoplasia type 2B (MEN2B), susceptibility to pheochromocytoma (PCC), multiple neoplasia type 2A (MEN2A), thyroid papillary carcinoma (TPC) and congenital central hypoventilation syndrome (CCHS).
RET抗体相关产品如下:
hz-0293Rs Rabbit anti-Rat IgG whole serum兔抗大鼠IgG抗血清
hz-0293M Mouse Anti-rat IgG小鼠抗大鼠IgG
hz-0293R Rabbit Anti-rat IgG兔抗大鼠IgG
hz-0295M Mouse Anti-rabbit IgG小鼠抗兔IgG
hz-0296R Rabbit Anti-mouse IgG兔抗小鼠IgG
hz-0335R Rabbit Anti-Monkey IgG兔抗猴IgG
hz-0346R Rabbit Anti-rat IgM兔抗大鼠IgM
hz-0369M Mouse Anti-Rabbit IgM小鼠抗兔IgM
hz-0346Rs Rabbit anti-Rat IgM whole serum兔抗大鼠IgM抗血清
hz-0295Gs Goat anti-Rabbit IgG whole serum羊抗兔IgG抗血清
hz-0295hzs Donkey anti-Rabbit IgG whole serum驴抗兔IgG抗血清
hz-0368G Goat Anti-Mouse IgM羊抗小鼠IgM
hz-0293G Goat Anti-rat IgG羊抗大鼠IgG
hz-0358G Goat Anti-Guinea pig IgG羊抗豚鼠IgG
hz-0345G Goat Anti-human IgM羊抗人IgM
hz-0294M Mouse Anti-Goat IgG小鼠抗羊IgG
hz-0312R Rabbit Anti-Avidin兔抗亲和素
hz-0311R Rabbit Anti-Biotin兔抗生物素抗体IgG
hz-0327R Rabbit Anti-Bovine IgM兔抗牛IgM
hz-0314R Rabbit Anti-chicken IgM兔抗鸡IgM
hz-0303R Rabbit Anti-dog IgG兔抗狗IgG
hz-0370R Rabbit Anti-Goat IgM兔抗羊IgM
hz-0358R Rabbit Anti-Guinea pig IgG兔抗豚鼠IgG
hz-0375R Rabbit Anti-Guinea pig IgM兔抗豚鼠IgM
hz-0308R Rabbit Anti-horse IgG兔抗马IgG
hz-0345R Rabbit Anti-human IgM兔抗人IgM
hz-0336R Rabbit Anti-Monkey IgM兔抗猴IgM
hz-0368R Rabbit Anti-mouse IgM兔抗小鼠IgM
hz-0330R Rabbit anti-mouse Kappa light chain兔抗小鼠k链
hz-0403R Rabbit anti-MG IgG兔抗长爪沙鼠IgG
hz-0777R Rabbit Anti-Mink IgG兔抗水貂IgG
hz-0297hz Donkey Anti-human IgG驴抗人IgG
hz-0295hz Donkey Anti-rabbit IgG驴抗兔IgG
hz-0358hz Donkey Anti-Guinea pig IgG驴抗豚鼠IgG
hzm-0297M Mouse Anti-human IgG(3D3)鼠抗人IgG单克隆抗体
四、标记二抗
编号 名 称
hz-0373R-hzE-hzy5.5 Dog IgM/PE-Cy5.5PE-Cy5.5标记的兔抗犬IgM抗体
hz-0373R-hzE-hzy7 Dog IgM/PE-Cy7PE-Cy7标记的兔抗犬IgM抗体
hz-0373R-AF350 Dog IgM/Alexa Fluor 350Alexa Fluor 350标记的兔抗犬IgM抗体
hz-0373R-AF488 Dog IgM/Alexa Fluor 488Alexa Fluor 488标记的兔抗犬IgM抗体