免疫原 :
Recombinant Human CD50 / ICAM-3 protein (Catalog#10333-H08H)
Antibody Type : Rabbit Monoclonal Antibody ( Rabbit mAb Service Platform )
克隆号 :
003
抗体宿主 :
Rabbit IgG
缓冲液 : 0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.
制备方法 :
This antibody was obtained from a rabbit immunized with purified, recombinant Human CD50 / ICAM-3 (rh CD50 / ICAM-3; Catalog#10333-H08H; NP_002153.2; Met1-His485).
CD50 / ICAM-3抗体 Background
The protein ICAM3, also known as CD50, is a member of the intercellular adhesion molecule (ICAM) family consisting three members. All ICAM proteins are type I transmembrane glycoproteins, and are ligands for leukocyte function-associated antigen 1 (LFA-1) expressed on the surface of all white blood cells. ICAM-3 comprises of five immunoglobulin-like domains, and binds LFA-1 through its two N-terminal domains. It functions not only as an adhesion molecule, but also as a potent signalling molecule.ICAM3 is constitutively and abundantly expressed by all leucocytes, and thus is the major ligand for LFA-1 in the initiation of primary immune responses. It has been reported that CD50 molecule can play a role in developing functionally mature T lymphocytes and its expression increases during the maturation process of T lymphocytes. In addition, the interactions of ICAM-3 and LFA-1 facilitate HIV-1- induced virological synapse formation between T cells.
CD50 / ICAM-3抗体相关产品如下:
hz-9513R Protein Z蛋白Z抗体
hz-9512R Protein S蛋白S抗体
hz-6984R PEBP2B多瘤病毒增强了结合蛋白2β抗体
hz-1325R PDE4D磷酸二酯酶4D抗体
hz-1875R Profilin 2前纤维蛋白2抗体
hz-1873R PRCP脯氨酰羧肽酶抗体
hz-1857R P2Y4P2Y4受体抗体
hz-1869R PEA3瘤促活化因子3抗体
hz-1436R PBP磷脂酰乙醇胺结合蛋白1抗体
hz-1527R peripherin外周蛋白抗体
hzm-1625M PSA(Pa3)人前列腺特异性抗原单克隆抗体(包被)
hzm-1626M PSA (PA5)鼠抗人前列腺特异性抗原单克隆抗体(检测)
hz-1449R Prohibitin抑制素/肿瘤抑制因子抗体
hz-1451R PAFAH脂蛋白磷脂酶A2抗体
hz-0362R Protein A重组金黄色葡萄球菌蛋白A抗体
hz-2395R Pescadillo雌激素受体共调节因子抗体
hz-1518R PersephinPSP抗体
hz-1515R Pan-rasPan ras抗体
hz-1614R PatchedPatched/PTCH抗体
hz-1880R PTGEs前列腺素E合成酶抗体
hz-1832R PPARGC1A过氧化物酶体增殖物激活受体γ辅激活子1α抗体
hz-3535R PLK1丝氨酸/苏氨酸蛋白激酶Plk1抗体
hz-3344R Phospho-PLK1 (Thr210)磷酸化丝/苏氨酸蛋白激酶Plk1抗体
hz-3536R PPIG亲环蛋白(亲环素)PPIG抗体
hz-3461R Phospho-PPIG (Ser376)磷酸化亲环蛋白(亲环素)PPIG抗体
hz-3346R Phospho-PRAS40 (Thr246)磷酸化蛋白激酶AKT底物1抗体
hz-3347R Phospho-PRK1(Thr774) + PRK2 (Thr816)磷酸化内分泌腺衍生血管内皮生长因子抗体
hz-3357R PYK2富含脯氨酸的酪氨酸激酶2抗体
hz-3400R phospho-PYK2 (Tyr402)磷酸化富含脯氨酸的酪氨酸激酶2抗体
hz-3401R phospho-PYK2 (Tyr881)磷酸化富含脯氨酸的酪氨酸激酶2抗体
hz-3362R Phospho-p90RSK (Ser380)磷酸化丝氨酸/苏氨酸激酶p90RSK蛋白抗体
hz-3363R Phospho-p90RSK (Thr359 + Ser363)磷酸化丝氨酸/苏氨酸激酶p90RSK蛋白抗体
hz-3364R Phospho-p90RSK (Thr573)磷酸化丝氨酸/苏氨酸激酶p90RSK蛋白抗体
hz-1828R Plasminogen纤维蛋白溶酶原抗体
hz-1995R p95 NBS1DNA修复蛋白NBS1抗体
hz-2512R PRMT1蛋白质精氨酸甲基转移酶1抗体
hz-2589R P450 1A2/CYP1A2细胞色素P450 1A2抗体
hz-3460R Phospho-PLC gamma 1 (Tyr771)磷酸化磷酯酶Cγ1抗体
hz-3342R Phospho-PLC gamma 1(Ser1248)磷酸化磷酯酶Cγ1抗体
hz-3343R Phospho-PLC γ1 (Tyr783)磷酸化磷酯酶Cγ1抗体
hz-3345R Phospho-PLK1 (Ser137)磷酸化丝/苏氨酸蛋白激酶Plk1抗体
hz-3355R Phospho-PNK1 (Ser114 + Thr118)磷酸化多聚合苷酸激酶3磷酸化酶抗体
hz-3538R PSD93突触后密度蛋白93抗体
hz-3348R Phospho-PSD93 (Tyr340)磷酸化突触后密度蛋白93抗体
hz-3349R Phospho-PSD95 (Tyr236 + Tyr240)磷酸化突触后密度蛋白95抗体
hz-3350R Phospho-PTEN(Ser380)磷酸化肿瘤抑制基因PTEN抗体