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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
4度,-20
- 保质期:
2年
- 英文名:
thermo
- 库存:
1000
- 供应商:
北诺生命科学
- 规格:
50 µg
货号 产品名称 规格 2013 目录价(¥)
K0331 Luminaris Color Probe High ROX qPCR Master Mix 250 x 20 µL rxns 1,355
K0332 Luminaris Color Probe High ROX qPCR Master Mix 500 x 20 µL rxns 2,510
K0333 Luminaris Color Probe High ROX qPCR Master Mix 1,250 x 20 µL rxns 5,744
K0334 Luminaris Color Probe High ROX qPCR Master Mix 5,000 x 20 µL rxns 16,034
K0341 Luminaris Color Probe Low ROX qPCR Master Mix 250 x 20 µL rxns 1,355
K0342 Luminaris Color Probe Low ROX qPCR Master Mix 500 x 20 µL rxns 2,510
K0343 Luminaris Color Probe Low ROX qPCR Master Mix 1,250 x 20 µL rxns 5,744
K0344 Luminaris Color Probe Low ROX qPCR Master Mix 5,000 x 20 µL rxns 16,034
K0351 Luminaris Color Probe qPCR Master Mix 250 x 20 µL rxns 1,355
K0352 Luminaris Color Probe qPCR Master Mix 500 x 20 µL rxns 2,510
K0353 Luminaris Color Probe qPCR Master Mix 1,250 x 20 µL rxns 5,744
K0354 Luminaris Color Probe qPCR Master Mix 5,000 x 20 µL rxns 16,034
K0361 Luminaris Color HiGreen High ROX qPCR Master Mix 250 x 20 µL rxns 1,355
K0362 Luminaris Color HiGreen High ROX qPCR Master Mix 500 x 20 µL rxns 2,510
K0363 Luminaris Color HiGreen High ROX qPCR Master Mix 1,250 x 20 µL rxns 5,744
K0364 Luminaris Color HiGreen High ROX qPCR Master Mix 5,000 x 20 µL rxns 16,034
K0371 Luminaris Color HiGreen Low ROX qPCR Master Mix 250 x 20 µL rxns 1,355
K0372 Luminaris Color HiGreen Low ROX qPCR Master Mix 500 x 20 µL rxns 2,510
K0373 Luminaris Color HiGreen Low ROX qPCR Master Mix 1,250 x 20 µL rxns 5,744
K0374 Luminaris Color HiGreen Low ROX qPCR Master Mix 5,000 x 20 µL rxns 16,034
K0381 Luminaris Color HiGreen Fluorescein qPCR Master Mix 250 x 20 µL rxns 1,355
K0382 Luminaris Color HiGreen Fluorescein qPCR Master Mix 500 x 20 µL rxns 2,510
K0383 Luminaris Color HiGreen Fluorescein qPCR Master Mix 1,250 x 20 µL rxns 5,744
K0384 Luminaris Color HiGreen Fluorescein qPCR Master Mix 5,000 x 20 µL rxns 16,034
K0391 Luminaris Color HiGreen qPCR Master Mix 250 x 20 µL rxns 1,355
K0392 Luminaris Color HiGreen qPCR Master Mix 500 x 20 µL rxns 2,510
K0393 Luminaris Color HiGreen qPCR Master Mix 1,250 x 20 µL rxns 5,744
K0394 Luminaris Color HiGreen qPCR Master Mix 5,000 x 20 µL rxns 16,034
K0441 TranscriptAid™ T7 High Yield Transcription Kit 50 react 2,325
K0512 Genomic DNA Purification Kit 100 preps 595
K0513 Silica Bead DNA Gel Extraction Kit 100 preps 541
K0621 DecaLabel™ DNA Labeling Kit 10 react 541
K0622 DecaLabel™ DNA Labeling Kit 30 react 1,352
K0651 Biotin DecaLabel™ DNA Labeling Kit 10 react 919
K0652 Biotin DecaLabel™ DNA Labeling Kit 30 react 2,271
K0661 Biotin Chromogenic Detection Kit 10 react 865
K0662 Biotin Chromogenic Detection Kit 30 react 1,947
K1071 DreamTaq™ PCR Master Mix (2X) 200 react 541
K1072 DreamTaq™ PCR Master Mix (2X) 1000 react 2,163
K1081 DreamTaq™ Green PCR Master Mix (2X) 200 react 541
K1082 DreamTaq™ Green PCR Master Mix (2X) 1000 react 2,163
K1091 Fast Tissue-to-PCR Kit 200 react 2,271
K1213 InsTAclone™ PCR Cloning Kit 10 react 649
K1214 InsTAclone™ PCR Cloning Kit 30 react 1,406
K1231 CloneJET™ PCR Cloning Kit 20 react 1,146
K1232 CloneJET™ PCR Cloning Kit 40 react 2,163
K1422 Rapid DNA Ligation Kit 50 react 1,179
K1423 Rapid DNA Ligation Kit 150 react 2,358
K1611 First Strand cDNA Synthesis Kit 20 react 595
K1612 First Strand cDNA Synthesis Kit 100 react 2,379
K1621 RevertAid™ First Strand cDNA Synthesis Kit 20 react 433
K1622 RevertAid™ First Strand cDNA Synthesis Kit 100 react 1,730
K1631 RevertAid™ H Minus First Strand cDNA Synthesis Kit 20 react 757
K1632 RevertAid™ H Minus First Strand cDNA Synthesis Kit 100 react 3,028
K1641 Maxima® First Strand cDNA Synthesis Kit 50 react 2,704
K1642 Maxima® First Strand cDNA Synthesis Kit 200 react 8,111
K1651 RevertAid™ Premium First Strand cDNA Synthesis Kit 20 react 1,049
K1652 RevertAid™ Premium First Strand cDNA Synthesis Kit 100 react 4,196
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文献和实验之所以令人鼓舞,在于发现了两种有望成为治疗靶标的蛋白质,可籍此预防恶性白血病的复发。该研究由英国癌症研究协会与白血病与淋巴瘤研究协会提供资金,将发表于《Cell Stem Cell》(2010年该刊影响因子为23.5左右——译者)。 本研究中科学家所关注的白血病干细胞发现于与MLL基因相关的一类血癌。这类血癌占幼儿白血病的70%、成人急性白血病的10%。儿童MLL预后差——接受标准治疗后超过两年的生存率只有50%。 已知Bmi1蛋白在各种肿瘤干细胞的生存与扩散中扮演着关键角色。但本研究
Cancer Stem Cells in Head and Neck Squamous Cell Carcinoma
in mice that recapitulates the original tumor heterogeneity. Furthermore, they have a primitive cellular morphology, express high levels of nuclear BMI1, and are arrayed in characteristic tumor microdomains. The methods used to purify this subset
。已知INK4a位点被多克隆抑制复合物(PRC1)抑制,Bim1是其中的一个重要成员。Bim1缺陷小鼠表现出早衰,Bim1-KO肌肉表现出高p16INK4a表达水平,这表明PRC1功能紊乱是p16INK4a去抑制的基础。视网膜母细胞瘤(Rb)蛋白很可能作用于p16INK4a下游,导致衰老。事实上,老年肌肉中p16INK4a的高表达水平与磷酸化Rb蛋白的降低有关。p16INK4在肌肉衰老中的作用被强调,当移植到小鼠体内时,它的沉默恢复了老年人和Bmi1阴性卫星细胞的增殖和自我更新能力。作者还揭示
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