Integrin beta 2 (ITGB2) (Activ

Integrin beta 2 (ITGB2) (Activation Site) 抗体
抗原
Integrin beta 2 (ITGB2)
别名 ITGB2, 2E6, AI528527, Cd18, LAD, LCAMB, Lfa1, MF17, CD18, LFA-1, MAC-1, MFI7, AI256028, LTbetaR, Ltar, TNF-R-III, TNFCR, TNFR-RP, TNFR2-RP, TNFRrp, Tnfbr, Tnfrsf3, D12S370, LT-BETA-R, TNFR3, TNFRSF3
抗原表位
其他选择 Activation Site
适用
其他选择 人
宿主
其他选择 小鼠
克隆类型 (克隆位点)
单克隆 (MEM-148)
Integrin beta 2 (ITGB2) (Activation Site) 抗体标记
其他选择 PE
应用范围
其他选择 流式细胞分析技术（FACS）
Pubmed 找到1个引用
规格 100 tests
发货至 中国 (更改)
产品细节
克隆位点 MEM-148
亚型 IgG1
特异性 This antibody recognises an epitope on the CD18 Molecule that is hidden in the CD11/CD18 heterodimer on resting cells. Clone MEM-148 binds very weakly to resting peripheral blood leukocytes and strongly to all leukocytes upon cellular activation. The epitope recognised by MEM-148 is also exposed during dissociation of the CD11/CD18 by low pH .
纯化方法 Affinity chromatography on Protein G
目标详细情况
别名 CD18 / ITGB2
背景 CD18 is an integrin. Integrins are integral cell surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA1, and combines with the alpha M chain to form the integrin Mac1. Integrins are known to participate in cell adhesion as well as cell surface mediated signalling. CD18 is expressed by most leucocytes. Defects in the CD18 gene result in leukocyte adhesion deficiency.Synonyms: 95 subunit beta, Cell surface adhesion glycoproteins LFA-1/CR3/p150, Complement receptor C3 subunit beta, Integrin beta-2, MFI7
Integrin beta 2 (ITGB2) (Activation Site) 抗体基因ID 3689
NCBI登录号 NP_000202
UniProt P05107
研究领域 CD Antigens, Surface Receptors of Immune Cells
使用细节
应用备注 Flow cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
限制 仅限研究用
贮存及处理
溶解方式 Restore with 1 mL distilled water
缓冲液 Contains 0.09 % Sodium Azide and 1 % Bovine Serum Albumin
储存液 Sodium azide
注意事项 Use of sodium azide as a preservative will substantially inhibit the enzyme activity of horseradish peroxidase.
注意事项 Avoid repeated freezing and thawing. Should this product contain a precipitate we recommend microcentrifugation before use.
储存条件 4 °C/-20 °C
储存方法 Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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