FZD7 抗体

FZD7 抗体
抗原
Frizzled Family Receptor 7 (FZD7)
别名 Fz-7, Xfz7, frizzled-7, frizzled7, frz-7, frz7, fz7, fze3, FzE3, fzd7-a, fzd7-b, cFz-7, Fz7
适用
其他选择 人, 小鼠, 大鼠, 小鸡, 犬, 猪, 牛, 豚鼠
宿主
其他选择 兔
克隆类型
多克隆
标记
其他选择 非结合性
应用范围
其他选择 Western Blotting (WB), 免疫组织化学石蜡技术（IHC-P）, 免疫萤光石蜡技术（IF-P）
规格 100 μL
FZD7 抗体发货至 中国 (更改)
产品细节
免疫原 KLH conjugated synthetic peptide derived from human Frizzled 7
亚型 IgG
交叉反应 大鼠, 小鸡, 犬, 猪, 牛, 豚鼠
纯化方法 purified by Protein A and peptide affinity chromatography
目标详细情况
别名 Frizzled 7
背景 Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The Frizzled 7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Frizzled family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. Frizzled 7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas. Frizzled 7 expression has been reported in brain, gastrointestinal tract, heart, fetal kidney, fetal lung, placenta, skeletal muscle, and various cancers. ESTs have been isolated from a wide variety of normal and cancer libraries.
分子量 90kDa
基因ID 8324
使用细节
应用备注 WB(1:100-500)
Optimal working dilution should be determined by the investigator.
限制 仅限研究用
FZD7 抗体贮存及处理
状态 Liquid
浓度 1 µg/µL
缓冲液 Aqueous buffered solution containing 100 µg/mL BSA, 50 % glycerol and 0.09 % sodium azide.
储存液 Sodium azide
注意事项 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件 -20 °C
储存方法 Store at -20 °C for 12 months
有效期 12 months
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