Ephrin-A2 / EFNA2抗体

Ephrin-A2 / EFNA2抗体产品信息免疫原 : Recombinant Mouse Ephrin-A2 / EFNA2 protein (Catalog#50579-M08H)

Antibody Type : Rabbit Polyclonal Antibody ( Antibody Purification Platform )
抗体宿主 : Rabbit IgG

缓冲液 : 0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.
制备方法 : Produced in rabbits immunized with purified, recombinant Mouse Ephrin-A2 / EFNA2 (rM Ephrin-A2 / EFNA2; Catalog#50579-M08H; NP_031935.3; Met 1-Asn 184). Total IgG was purified by Protein A affinity chromatography.
Ephrin-A2 / EFNA2抗体 Background
Ephrin-A2, also known as EPH-related receptor tyrosine kinase ligand 6, LERK-6, HEK7 ligand, EFNA2 and EPLG6, is a cell membrane protein which belongs to the ephrin family. Ephrin-A2 / EFNA2 binds to the receptor tyrosine kinases EPHA3, EPHA4 and EPHA5. The ephrins (EPH) and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases (RTKs), and have been involved in a variety of biological processes, especially in the nervous system and in erythropoiesis, such as axon guidance and topographic map formation, synaptic plasticity, angiogenesis, and meanwhile have possible contributions to tumor growth and metastasis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class which are anchored to the membrane by a GPI linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. 14 receptors and 8 ligands have been reported in mammals.
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