- ￥3000 - 3999
- Abbiotec
- 美国
- 254505
- 2026年01月12日
- IF
- Rabbit
- H, M, R, B, Sh, P, D, Rb
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human Sox2.
- 亚型：
Rabbit Ig
- 形态：
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 2% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
- 保存条件：
Store at 4°C.
- 克隆性：
多克隆
- 标记物：
见下方详细说明
- 适应物种：
H, M, R, B, Sh, P, D, Rb
- 宿主：
Rabbit
- 应用范围：
IF
- 浓度：
见详细说明信息
- 靶点：
Sox2
- 抗体英文名：
Sox2 Antibody
- 抗体名：
Sox2 Antibody
- 规格：
0.1 mg
Sox2 Antibody产品详细介绍：
| 产品名称： | Sox2 Antibody |
| 说明书： | 【点击查看详细说明及参考图片】 |
| 货号： | 254505 |
| 规格： | 0.1 mg |
| 产品描述： | Transcription factor SOX-2 (Sox2) forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Defects in Sox2 are the cause of microphthalmia syndromic type 3 (MCOPS3). Microphthalmia is a clinically heterogeneous disorder of eye formation, ranging from small size of a single eye to complete bilateral absence of ocular tissues (anophthalmia). In many cases, microphthalmia/anophthalmia occurs in association with syndromes that include non-ocular abnormalities. POU5F1/OCT4, Sox2, MYC/c-Myc and KLF4 are the four Yamanaka factors. When combined, these factors are sufficient to reprogram differentiated cells to an embryonic-like state designated iPS (induced pluripotent stem) cells. iPS cells exhibit the morphology and growth properties of ES cells and express ES cell marker genes. |
| 克隆类型： | Rabbit Polyclonal Antibody, FITC-conjugated Antibody |
| 亚型： | Rabbit Ig |
| 免疫原： | KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human Sox2. |
| 适用物种： | H, M, R, B, Sh, P, D, Rb |
| 应用范围： | IF |
| 应用说明： | IF: 1:20-1:100 |
| 别名： | Transcription factor SOX-2; SOX2; SOX-2 |
| 形态： | Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 2% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography. |
| 保存条件： | Store at 4°C. Product is guaranteed 6 months from the date of shipment. |
| 参考文献： |
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文献和实验Generation of Antibody Molecules Through Antibody Engineering
been overcome to a large extent using genetic-engineering techniques to produce chimeric mouse/human and completely human antibodies. Such an approach is particularly suitable because of the domain structure of the antibody molecule ( 2 ), where functional
Induced Pluripotent Stem Cells (iPSC) from Cord Blood CD133+ Cells Using Oct4 and Sox2
only two transcription factors OCT4 and SOX2. The methods for establishment and maintenance of CB-derived iPS (CB-iPS) cells are similar, with some modifications, to those for human iPSCs derived from fibroblasts. In particular, this protocol includes a detailed
The importance of antibody molecules was first recognized in the 1890s, when it was shown that immunity to tetanus and diphtheria was caused by antibodies against the bacterial exotoxins (1 ). Around the same time, it was shown that antisera
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