SCN1A Antibody
Cat#:PL0305090
Isotype:Rabbit Polyclonal IgG
Immunogen:Peptide derived from human SCN1A.
Purification: Immunogen affinity purified
Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background:
SCN1A is a voltage-gated ion channel essential for the generation and propagation of action potentials, mainly in nerve and muscle. Voltage-sensitive sodium channels are heteromeric complexes consisting of a large central pore-forming glycosylated alpha subunit, and two smaller auxiliary beta subunits. This gene encodes the large alpha subunit, and mutations in this gene have been associated with several epilepsy, convulsion and migraine disorders. Alternative splicing results in multiple transcript variants. The RefSeq Project has decided to create four representative RefSeq records.
Alternate Names:
alpha; brain sodium channel type I; EIEE6; FEB3; FEB3A; FHM3; GEFS+2; GEFSP2; HBSC I; HBSCI; MIM 182390; NAC1; Nav 1.1; RBI; SCN1; Scn1a; SCN1A_HUMAN; SCN2A1; SMEI; sodium channel; Sodium channel protein brain I alpha subunit; Sodium channel protein brain I subunit alpha; Sodium channel protein type 1 subunit alpha; Sodium channel protein type I subunit alpha; Sodium channel voltage gated type 1 alpha subunit; Sodium channel voltage gated type I alpha polypeptide; type I; voltage gated; Voltage-gated sodium channel subunit alpha Nav1.1.
Specificity Reaction:Hu, Mo, Rat, Dog, Cow, Hor,
Application Notes:WB: 1:100-500 E: 1:500-1000 IP: 1:20-100 IHC: 1:100-500 IF: 1:100-500
Storage :
Store at –20ºC for one year. Avoid repeated freeze-thaw cycles. At 4ºC for 2-3 weeks after reconstituted.
This product for research use only, not for use in humans, therapeutic or diagnostic procedures.
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