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CDO1 Antibody

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  • ¥2400
  • PLLABS已认证
  • 加拿大
  • PL0302404
  • 2025年07月16日
  • WB: 1:100-500 E: 1:500-1000 IP: 1:20-100 IHC: 1:100-500 IF: 1:100-500
  • Rabbit
  • Hu, Mo, Rat, Chi, Dog, Cow, Hor, Sheep
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 免疫原

      Peptide derived from human CDO1.

    • 亚型

      Rabbit Polyclonal IgG

    • 形态

      液态

    • 保存条件

      保存于-20℃

    • 克隆性

      多克隆

    • 标记物

      无标记(PLlabs可供应生物素、酶、荧光素标记的抗体)

    • 适应物种

      Hu, Mo, Rat, Chi, Dog, Cow, Hor, Sheep

    • 保质期

      按说明书条件可保存1-2年

    • 抗原来源

      见详细说明资料

    • 目录编号

      PL0302404

    • 级别

      超纯

    • 库存

      大量

    • 供应商

      华拓生物

    • 宿主

      Rabbit

    • 应用范围

      WB: 1:100-500 E: 1:500-1000 IP: 1:20-100 IHC: 1:100-500 IF: 1:100-500

    • 浓度

      1mg/ml

    • 靶点

      CDO1

    • 抗体英文名

      CDO1 Antibody

    • 抗体名

      半胱氨酸双加氧酶1抗体

    • 规格

      0.1ml

    产品细节图片1
    CDO1 Antibody
    Cat#:PL0302404
    Isotype:Rabbit Polyclonal IgG
    Immunogen:Peptide derived from human CDO1.
    Purification: Immunogen affinity purified

    Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)

    Background:
    CDO1 (cysteine dioxygenase, type I) is a 200 amino acid protein that belongs to the cysteine dioxygenase family and is involved in organosulfur biosynthesis. Existing as a monomer and expressed at high levels in liver and placenta and at lower levels in brain, pancreas and heart, CDO1 functions as a dioxygenase that uses iron and zinc as cofactors to catalyze the conversion of L-cysteine and oxygen to 3-sulfinoalanine. Via its catalytic activity, CDO1 is involved in pyruvate-, sulfate- and taurine-related metabolic pathways and is a crucial regulator of cysteine concentrations within the cell. Human CDO1 shares 94% amino acid identity with its rat counterpart, suggesting a conserved role between species. The gene encoding CDO1 maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome.
    Alternate Names:
    Cysteine Dioxygenase Type 1; CDO 1; CDO; CDO I; CDO1; CDO-1; CDOI; Cytosolic cysteine dioxygenase; CDO1_HUMAN.
    Specificity Reaction:Hu, Mo, Rat, Chi, Dog, Cow, Hor, Sheep
    Application Notes:WB: 1:100-500 E: 1:500-1000 IP: 1:20-100 IHC: 1:100-500 IF: 1:100-500
    Storage :
    Store at –20ºC for one year. Avoid repeated freeze-thaw cycles. At 4ºC for 2-3 weeks after reconstituted.

    This product for research use only, not for use in humans, therapeutic or diagnostic procedures.
    PLlabs公司可供应相应抗体的生物素、辣根过氧化物酶、荧光素(FITC、PE、 CY3、 CY5、 CY7、 PE- CY3/5/7)标记抗体,欢迎大家咨询订购。

    产品细节图片2 产品细节图片3 产品细节图片4
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    图标文献和实验
    相关实验
    • ​Nat Metab:汤其群 / 郭亮团队发现半胱氨酸双加氧酶促进脂肪分解的新功能

      。 2022 年 10 月 17 日,汤其群/郭亮团队在 Nature Metabolism 上发表了题为 Cdo1 promotes PPARγ-mediated adipose tissue lipolysis in male mice 的研究成果。该研究发现,脂肪组织 Cdo1 受到寒冷诱导上调,能够通过 PPARγ/Med24/lipolysis 信号通路,转录激活脂解基因 ATGL 和 HSL 的表达,从而增加小鼠脂肪组织脂解、寒冷耐受能力和能量消耗,进一步抵抗小鼠肥胖及代谢紊乱。 研究团队

    • Generation of Antibody Molecules Through Antibody Engineering

      been overcome to a large extent using genetic-engineering techniques to produce chimeric mouse/human and completely human antibodies. Such an approach is particularly suitable because of the domain structure of the antibody molecule ( 2 ), where functional

    • The Antibody Molecule

      The importance of antibody molecules was first recognized in the 1890s, when it was shown that immunity to tetanus and diphtheria was caused by antibodies against the bacterial exotoxins (1 ). Around the same time, it was shown that antisera

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