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phospho-c-Jun(Ser243) Antibody

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  • ¥2400
  • PLLABS已认证
  • 加拿大
  • PL0302156
  • 2025年07月13日
  • WB: 500-1000 E: 1:2000-5000 IHC: 1:100-500 IF: 1:100-500
  • Rabbit
  • Hu, Mo, Rat, Chi, Dog, Pig, Cow, Hor, Sheep,
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 免疫原

      PhosphoPeptide derived from human c-Jun around the phosphorylation site of Ser73.

    • 亚型

      Rabbit Polyclonal IgG

    • 形态

      液态

    • 保存条件

      保存于-20℃

    • 克隆性

      多克隆

    • 标记物

      无标记(PLlabs可供应生物素、酶、荧光素标记的抗体)

    • 适应物种

      Hu, Mo, Rat, Chi, Dog, Pig, Cow, Hor, Sheep,

    • 保质期

      按说明书条件可保存1-2年

    • 抗原来源

      见详细说明资料

    • 目录编号

      PL0302156

    • 级别

      超纯

    • 库存

      大量

    • 供应商

      华拓生物

    • 宿主

      Rabbit

    • 应用范围

      WB: 500-1000 E: 1:2000-5000 IHC: 1:100-500 IF: 1:100-500

    • 浓度

      1mg/ml

    • 靶点

      phospho-c-Jun(Ser243)

    • 抗体英文名

      phospho-c-Jun(Ser243) Antibody

    • 抗体名

      磷酸化原癌基因c-Jun抗体

    • 规格

      0.1ml

    产品细节图片1
    phospho-c-Jun(Ser243) Antibody
    Cat#:PL0302156
    Isotype:Rabbit Polyclonal IgG
    Immunogen:PhosphoPeptide derived from human c-Jun around the phosphorylation site of Ser73.
    Purification: Immunogen affinity purified

    Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)

    Background:
    C-jun (Oncoprotein C-jun) is a component of the transcription factor AP-1 that binds and activates transcription at TRE/AP-1 elements and appears to be a major downstream target of the SAPK/JNK signaling pathway. The transcriptional activity of c-Jun is regulated by phosphorylation at Ser63 and Ser73. Extracellular signals including growth factors, transforming oncoproteins and UV irradiation stimulate phosphorylation of c-Jun at Ser63/73 and activate c-Jun dependent transcription. Mutation of Ser63/73 renders c-Jun nonresponsive to mitogenic and stress induced signaling pathways.
    Alternate Names:
    c-Jun (phospho S243); c-Jun(Phospho-Ser243); Jun oncogene; JUN; Activator Protein 1; AP 1; AP1; AP-1; Enhancer Binding Protein AP1; Jun Activation Domain Binding Protein; JUN protein; JUNC; p39; Proto oncogene cJun; Transcription Factor AP1; V jun avian sarcoma virus 17 oncogene homolog; vJun Avian Sarcoma Virus 17 Oncogene Homolog; JUN_HUMAN; Transcription factor AP-1; Activator 1; Proto-oncogene c-Jun; V-jun avian sarcoma virus 17 oncogene homolog.
    Specificity Reaction:Hu, Mo, Rat, Chi, Dog, Pig, Cow, Hor, Sheep,
    Application Notes:WB: 500-1000 E: 1:2000-5000 IHC: 1:100-500 IF: 1:100-500
    Storage :
    Store at –20ºC for one year. Avoid repeated freeze-thaw cycles. At 4ºC for 2-3 weeks after reconstituted.

    This product for research use only, not for use in humans, therapeutic or diagnostic procedures.
    PLlabs公司可供应相应抗体的生物素、辣根过氧化物酶、荧光素(FITC、PE、 CY3、 CY5、 CY7、 PE- CY3/5/7)标记抗体,欢迎大家咨询订购。

    产品细节图片2 产品细节图片3 产品细节图片4
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    图标文献和实验
    相关实验
    • 【求助】如何选择C-JUN抗体

      . These residues (Ser 63 and 73) are required to be phosphorylated for efficient transactivation function. The kinases responsible for this modification in vivo are the SAPK/JNKs. These kinases bind with very high affinity to a region in c-Jun termed the delta

    • Using Phospho‐Motif Antibodies to Determine Kinase Substrates

      comprising both the phosphorylated residue and the surrounding residues that determine kinase specificity, with degenerate residues taking up the remaining positions. Currently, several categories of phospho?motif antibody are commercially available

    • Optimized Protocol to Make Phospho-Specific Antibodies that Work

      , not simply its level of expression. In this review, we will discuss both the design of the phosphopeptide immunogen and immunization. The affinity purification of the phospho-specific antibody as well as the methods most suitable for characterizing

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