手机验证
询价列表
暂时没有已询价产品
微信扫一扫分享
分享到新浪微博
分享到丁香园论坛
TZ9
企业认证
点击 QQ 联系
Powder: -20°C, 3 years; 4°C, 2 years. In solvent: -80°C, 6 months; -20°C, 1 month.
货期:1-2天
MedChemExpress LLC
10 mM * 1 mL/5 mg/10 mg/50 mg/100 mg
MCE 的所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务。
CAS No. : 1002789-86-7
MCE 国际站:TZ9
产品活性:TZ9 是一种选择性的 Rad6 抑制剂。TZ9 能抑制 Rad6B 诱导的组蛋白 H2A 泛素化,下调细胞内 β-catenin,诱导 G2-M 停滞和凋亡,并抑制转移性人类乳腺癌细胞的增殖和迁移。
研究领域:Metabolic Enzyme/Protease | Apoptosis
作用靶点:E1/E2/E3 Enzyme | Apoptosis
In Vitro: TZ9 (Rad6B SMI #9) (0.5-100 µM; 72 h) inhibits MDA-MB-231 cell proliferation and migration.TZ9 (0.1-5 µM; 24-72 h) delays cell-cycle progression in MDA-MB-231 cells.TZ9 (5 µM; 8-48 h) induces apoptosis in MDA-MB-231 cells.TZ9 (0.5, 1, 2.5, 5 µM; 24 h) inhibits H2A ubiquitination and downregulates levels of PCNA and β-catenin protein in MDA-MB-231 cells.
相关产品:Bioactive Compound Library Plus | Apoptosis Compound Library | Metabolism/Protease Compound Library | Anti-Cancer Compound Library | Oxygen Sensing Compound Library | Ubiquitination Compound Library | Anti-Breast Cancer Compound Library | Anti-Liver Cancer Compound Library | Highly Selective Inhibitors Library | Highly Selective Activators Library | Cell Death Library | MG-132 | Doxorubicin hydrochloride | Bafilomycin A1 | LY294002 | Tamoxifen | Paclitaxel | Y-27632 | Acetylcysteine | Angiotensin II human | 2-Deoxy-D-glucose | Staurosporine | SB-431542 | Actinomycin D | Deferoxamine mesylate | Bortezomib | 5-Fluorouracil | Trametinib | Sorafenib | Oxaliplatin | Gemcitabine | Temozolomide | Rotenone | Mdivi-1 | Elesclomol | Ruxolitinib | Decitabine | SP600125 | MK-2206 dihydrochloride | Etoposide | Monomethyl auristatin E
热门产品线:重组蛋白 | 化合物库 | 天然产物 | 荧光染料 | PROTAC | 同位素标记物
Trending products:Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Dye Reagents | PROTAC | Isotope-Labeled Compounds
风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。
马上登录 或注册,即可保存询价历史