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- 艾美捷Prospec
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- PRO-551
- 2025年07月16日
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- 详细信息
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- 技术资料
- 保存条件：
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- 英文名：
Human Alpha-2 Macroglobulin Protein
- 库存：
100
- 供应商：
艾美捷科技
- 规格：
1mg///200ug
【A2M】人a-2巨球蛋白，Human Alpha-2 Macroglobulin Protein，A2M
产品名称：【A2M】人a-2巨球蛋白-Human Alpha-2 Macroglobulin Protein 产品货号：PRO-551 产品规格：1mg///200ug 来源宿主：人血浆中提取纯化
保存建议：【A2M】人a-2巨球蛋白-Human Alpha-2 Macroglobulin ProteinHuman Alpha-2 Macroglobulin although stable at room temperature for 3 weeks， should be stored between 2-8℃.
背景资料：Alpha-2 Macroglobulin is a serine proteases inhibitor， which inhibits coagulation by inactivating thrombin and Kallikrein， it inhibits fibrinolysis by inactivating plasmin and involved in insulin transport. Alpha-2-Macroglobulin is a large plasma protein， which is produced by the liver， it’s composed of 4 identical subunits bound together by -S-S- bonds. A2M is able to inactivate many kinds of proteinases （including serine-， cysteine-， aspartic- and metalloproteinases）. ?2M has a 35 amino acid "bait" region in its structure. Proteinases bind and cleave the “bait” region become bound to ?2M. Macrophage receptors recognize the proteinase-?2M complex and clear it from the system. A2M binds to and removes MMP-2 and MMP-9 （active forms of the gelatinase） from the circulation using scavenger receptors on the phagocytes. The levels of Alpha-2-macroglobulin are increased in nephrotic syndrome which is a condition where the kidneys start to leak out some of the smaller blood proteins. Due to its large size， ?2-macroglobulin is retained in the bloodstream. Increased production of all proteins causes ?2-macroglobulin concentration to increase. Chronic renal failure might lead to amyloid by alpha-2-macroglobulin. A2M is raised in cirrhosis， pregnancy and diabetes.
点击：【A2M】人a-2巨球蛋白-Human Alpha-2 Macroglobulin Protein查看更详细产品说明，更多应用、储存、价格、货期等信息请致电垂询艾美捷科技有限公司。更多prospec公司特色试剂盒、特色抗体以及特色试剂等产品评论，请点击查看艾美捷特色产品中心。
ProSpec 是一家全球著名细胞因子蛋白生产和研发的公司，具有20多年的生产经验，专注于蛋白（重组及合成）生产研发。我们的核心产品包括：干扰素、白介素、骨蛋白、肿瘤坏死因子、成纤维生长因子、瘦素、干细胞因子、催乳素、表皮生长因子、胰岛素样生长因子、神经生长因子、集落刺激因子、激素、酶、病毒抗原以及各种重组蛋白等。领先的生产工艺和规模使其可以提供毫克到克级蛋白，价格优于同类公司。绝大部分产品是天然成熟型蛋白，而不含有标签蛋白。考虑到大部分研究者希望能更灵活地配制蛋白溶液，ProSpec-Tany绝大部分产品没有添加保护剂或盐，这就对工艺提出了更高的要求。同时，ProSpec-Tany绝大部分产品为冻干粉，因此易于运输和保存。
艾美捷科技有限公司，通过提供完整的产品和服务体系、便利的客户关系和供应链管理，为生命科学研究工作者提供整体打包方案。我们的企业的核心价值观:“学习、创新、合作、卓越"。作为一家具有尖端的技术实力、的经营管理水平和完善的市场销售体系的生物高科技企业，总部位于武汉光谷高新技术开发区，服务面向全国。艾美捷科技是集进口试剂、实验室耗材销售、技术服务与合约开发为一体的专业化高科技公司，为用户提供最前沿的专业资讯、完备的产品、整合的解决方案，及优质的物流服务。为了更好的服务客户，公司组建了一支经验丰富的研发团队-艾美捷生物技术中心，进入研发生产阶段，将更优质的产品推荐给国内生物领域的同仁们!
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文献和实验Evaluation of the Cardiac Isoform of 2-Macroglobulin as a Factor Inducing Cardiac Hypertrophy
is a cardiac isoform of α2 -macroglobulin belonging to the macro-globulin family. Furthermore, it has been demonstrated that direct injection of the purified 182-kDa protein intravenously (through the tail vein) into the normal animals led to the development
LABELING ALPHA-ACTININ WITH IATR
.Dialyze overnight against buffer 5 in the cold room. 11.Clarify at 25,000 rpm,4℃,for 20 min in a 42.2Ti rotor. 12.Determine the concentration of alpha-actinin using Lowry assay.Determine dye/protein molar ratio by diluting conjugate 1:40 (10μl in 400μl
Measurements of DNA Immobilized in the Alpha-Hemolysin Nanopore
In the past decade, there have been extensive studies aimed at exploring the potential of protein nanopores to sequence single strands of DNA using resistive pulse sensing. The high speed of DNA electrophoretically driven through these pores
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