CD3抗体（克隆号OKT3）|CD3 Antibody （C

产品名称：CD3抗体（克隆号OKT3）|CD3 Antibody （Clone OKT3） （CD3）

【产品形式】：艾美捷为您提供的CD3抗体（克隆号OKT3）产品为无色溶液形式，含有100 ug抗体.该产品浓度为0.5 mg/ml，溶解于包含有0.05% BSA和0.05%NaN3的PBS缓冲液中.请在收到该CD3抗体（克隆号OKT3）产品后，将其置于-20 °C冷冻保存，建议分装使用以避免反复冻融.

【背景资料】：CD3 （T3）， a complex T cell marker， is known to associate noncovalently with the a/b or g/z heterodimer of the T cell antigen receptor （TCR） to form the most complex transmembrane （TM） receptor structures. Structurally， CD3 consists of four distinct membrane glycoprotein isoforms （CD3g， CD3e， CD3s and the zeta chain） to generate activation signals. CD3 is specially engaged in antigen recognition and is known to play an important role in mediating signals that are critical for T cell development in the thymus， proliferation， and induction of T cell-mediated immune responses against infectious agents and also in the differentiation of T cells into effector and memory populations. CD3 usually expresses in the cytoplasm of prothymocytes， and on the surface of about 95% of thymocytes， but cytoplasmic CD3 is lost as the cells differentiate into medullary thymocytes. Apart from its role as an important marker in the classification of malignant lymphomas and lymphoid leukemia， CD3 can also be useful for the identification of T cells in celiac disease， lymphocytic colitis and colorectal carcinomas associated with loss of a mismatch repair protein. CD3 indirectly plays an important role in immunomodulation whereas the anti-CD3 antibody may be used in in vitro Treg assays to generate effector T cells.

BioVision的公司总部在美丽的旧金山湾地区，它是全球生命科学公司的领导者.BioVision在开发和研究细胞凋亡检测分析、代谢检测方面具有 卓越的影响力.包括检测各种检测分析试剂盒、相关特色抗体、重组蛋白及细胞因子和酶等多种产品，以及其他创新的研究工具.其产品覆盖细胞凋亡研究、能量代 谢、细胞/组织蛋白提取、氧化应激与损伤、代谢与肥胖症、细胞增殖与毒性、信号转导、干细胞研究等领域.作为多家知名品牌的中国总代理以及中国区域代理， 艾美捷与BioVision一起为研究者们提供最好、最新的细胞生物学研究工具而不断扩大产品及服务质量.

点击：CD3抗体（克隆号OKT3），查看更详细产品说明，更多应用、储存、价格、货期等信息请致电400-6800-868垂询BioVision中国区域授权总代理艾美捷科技有限公司。

关键词：CD3，CD3抗体（克隆号OKT3）